Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human SCN4B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120734.10
The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10...
| Keywords: | SCN4B, Sodium channel subunit beta-4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 25 kD |
From 1,185.00€
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Human CAC1C-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120736.10
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists...
| Keywords: | CACH2, CACNA1C, Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-dependent L-type calcium channel subunit... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 249 kD |
From 1,185.00€
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Human CAC1A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120739.10
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta,...
| Keywords: | BI, CACH4, Brain calcium channel I, Voltage-gated calcium channel subunit alpha Cav2.1, Calcium channel, L type, alpha-1... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 282.6 kD |
From 1,185.00€
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Human CAC1H-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120743.10
This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio....
| Keywords: | Voltage-gated calcium channel subunit alpha Cav3.2, Low-voltage-activated calcium channel alpha1 3.2 subunit,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 259.2 kD |
From 1,185.00€
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Human CNGA3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120747.10
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different...
| Keywords: | CNG3, CNCG3, CNGA3, CNG-3, CNG channel alpha-3, Cyclic nucleotide-gated channel alpha-3, Cyclic nucleotide-gated cation... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 78.8 kD |
From 1,185.00€
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Human CNGA4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120748.10
CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).[supplied by OMIM, Mar 2008]. Human CNGA4-Strep full length protein-synthetic nanodisc. Protein function: Second messenger, cAMP, causes the opening of cation-...
| Keywords: | CNG4, CNGA4, CNG-4, CNG channel alpha-4, Cyclic nucleotide-gated channel alpha-4, Cyclic nucleotide-gated cation channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 66 kD |
From 1,185.00€
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Human CNGB3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120750.10
This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with...
| Keywords: | CNGB3, CNG channel beta-3, Cyclic nucleotide-gated channel beta-3, Cyclic nucleotide-gated cation channel beta-3, Cone... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 92.2 kD |
From 1,185.00€
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Human HCN1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120751.10
The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for...
| Keywords: | HCN1, BCNG1, BCNG-1, Brain cyclic nucleotide-gated channel 1, Potassium/sodium hyperpolarization-activated cyclic... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 98.8 kD |
From 1,185.00€
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Human HCN2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120752.10
The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of...
| Keywords: | HCN2, BCNG2, BCNG-2, Brain cyclic nucleotide-gated channel 2, Potassium/sodium hyperpolarization-activated cyclic... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 97 kD |
From 1,185.00€
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Human HCN3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120753.10
This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]. Human...
| Keywords: | HCN3, KIAA1535, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 86 kD |
From 1,185.00€
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Human HCN4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120754.10
This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have...
| Keywords: | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 129 kD |
From 1,185.00€
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Human TRPC3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120756.10
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular...
| Keywords: | TRP3, TrpC3, TRP-3, hTrp3, TRPC3, hTrp-3, Transient receptor protein 3, Short transient receptor potential channel 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 96 kD |
From 1,185.00€
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