Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human KCIP4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120699.10
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the...
| Keywords: | CALP, KCNIP4, KChIP4, Calsenilin-like protein, Kv channel-interacting protein 4, Potassium channel-interacting protein 4,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 28.7 kD |
From 1,185.00€
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Human KCNH6-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120700.10
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth...
| Keywords: | ERG2, ERG-2, hERG2, KCNH6, hERG-2, Eag-related protein 2, Ether-a-go-go-related protein 2, Ether-a-go-go-related gene... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 109.9 kD |
From 1,185.00€
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Human GL1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120701.10
This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4....
| Keywords: | POLR2M, GRINL1A, DNA-directed RNA polymerase II subunit M, isoforms 4/5, DNA-directed RNA polymerase II subunit GRINL1A,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 15.1 kD |
From 1,185.00€
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Human GRL1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120702.10
This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4....
| Keywords: | POLR2M, GRINL1A, Glutamate receptor-like protein 1A, DNA-directed RNA polymerase II subunit M, DNA-directed RNA polymerase... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 41.7 kD |
From 1,185.00€
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Human TM40-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120704.10
Potential channel-forming protein implicated in import of protein precursors into mitochondria.[UniProtKB/Swiss-Prot Function]. Human TM40-Strep full length protein-synthetic nanodisc. Protein function: Potential channel-forming protein implicated in import of protein precursors into mitochondria. [The UniProt...
| Keywords: | TOMM40B, TOMM40L, Protein TOMM40-like, Mitochondrial import receptor subunit TOM40B |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 33.9 kD |
From 1,185.00€
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Human KCNH7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120706.10
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth...
| Keywords: | ERG3, ERG-3, KCNH7, hERG-3, Eag-related protein 3, Ether-a-go-go-related protein 3, Voltage-gated potassium channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 135 kD |
From 1,185.00€
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Human KCD12-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120709.10
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).[UniProtKB/Swiss-Prot Function]. Human KCD12-Strep...
| Keywords: | Pfetin, KCTD12, C13orf2, Predominantly fetal expressed T1 domain, BTB/POZ domain-containing protein KCTD12 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 35.7 kD |
From 1,185.00€
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Human KCNG3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120715.10
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth...
| Keywords: | KCNG3, Voltage-gated potassium channel subunit Kv6.3, Voltage-gated potassium channel subunit Kv10.1, Potassium... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 49.6 kD |
From 1,185.00€
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Human BEST4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120719.10
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant...
| Keywords: | BEST4, VMD2L2, Bestrophin-4, Vitelliform macular dystrophy 2-like protein 2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 53.5 kD |
From 1,185.00€
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Human SCN8A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120727.10
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in...
| Keywords: | MED, SCN8A, Sodium channel protein type 8 subunit alpha, Sodium channel protein type VIII subunit alpha, Voltage-gated... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 225.3 kD |
From 1,185.00€
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Human SCN1B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120731.10
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel...
| Keywords: | SCN1B, Sodium channel subunit beta-1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 24.7 kD |
From 1,185.00€
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Human SCN2B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120732.10
The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. [provided by RefSeq, Jul 2015]....
| Keywords: | SCN2B, Sodium channel subunit beta-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 24.3 kD |
From 1,185.00€
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