Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human NMD3A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120837.10
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat....
| Keywords: | NR3A, GRIN3A, GluN3A, NMDAR3A, NMDAR-L, KIAA1973, Glutamate receptor ionotropic, NMDA 3A, N-methyl-D-aspartate receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 125.5 kD |
From 1,185.00€
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Human NMD3B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120838.10
The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia. [provided...
| Keywords: | NR3B, GRIN3B, GluN3B, NMDAR3B, Glutamate receptor ionotropic, NMDA 3B, N-methyl-D-aspartate receptor subtype 3B |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 113 kD |
From 1,185.00€
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Human GRIA1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120839.10
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a...
| Keywords: | GRIA1, GLUH1, GluA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor 1, AMPA-selective glutamate receptor 1, Glutamate... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 101.5 kD |
From 1,185.00€
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Human GRIA4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120842.10
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of...
| Keywords: | GLUR4, GluA4, GluR4, GluR-4, GluR-D, Glutamate receptor 4, AMPA-selective glutamate receptor 4, Glutamate receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 100.9 kD |
From 1,185.00€
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Human GRIK1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120843.10
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion...
| Keywords: | EAA3, GluK1, GLUR5, GRIK1, GluR5, GluR-5, Glutamate receptor 5, Excitatory amino acid receptor 3, Glutamate receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 104 kD |
From 1,185.00€
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Human GRIK2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120844.10
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion...
| Keywords: | EAA4, GRIK2, GluR6, GluK2, GLUR6, GluR-6, Glutamate receptor 6, Excitatory amino acid receptor 4, Glutamate receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 102.6 kD |
From 1,185.00€
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Human GRIK3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120845.10
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion...
| Keywords: | EAA5, GluK3, GluR7, GLUR7, GRIK3, GluR-7, Glutamate receptor 7, Excitatory amino acid receptor 5, Glutamate receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 104 kD |
From 1,185.00€
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Human MBP-CLDN6 full length protein-synthetic nanodisc
Item number: DIM-FLP110008.10
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking...
| Keywords: | CLDN6, Skullin, Claudin-6 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 63.3 kD |
From 1,317.00€
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Human MBP-AGTR1 full length protein-synthetic nanodisc
Item number: DIM-FLP110098.10
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major...
| Keywords: | AT1, AT1BR, AGTR1, AT1AR, AGTR1A, Type-1 angiotensin II receptor, Angiotensin II type-1 receptor |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 81.1 kD |
From 1,317.00€
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Human CXA8-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120632.10
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts,...
| Keywords: | Cx50, GJA8, Connexin-50, Lens fiber protein MP70, Gap junction alpha-8 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 48.2 kD |
From 1,185.00€
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Human CXB2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120634.10
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions...
| Keywords: | GJB2, Cx26, Connexin-26, Gap junction beta-2 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 26.2 kD |
From 1,185.00€
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Human KCNE1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120637.10
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product...
| Keywords: | KCNE1, Minimal potassium channel, Delayed rectifier potassium channel subunit IsK, Potassium voltage-gated channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 14.7 kD |
From 1,185.00€
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