Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
No results were found for the filter!
Human GBRB2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120807.10
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2...
| Keywords: | GABRB2, GABA(A) receptor subunit beta-2, Gamma-aminobutyric acid receptor subunit beta-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 59.2 kD |
From 1,185.00€
*
Human GBRB3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120808.10
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of...
| Keywords: | GABRB3, GABA(A) receptor subunit beta-3, Gamma-aminobutyric acid receptor subunit beta-3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 54.1 kD |
From 1,185.00€
*
Human GBRD-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120809.10
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor...
| Keywords: | GABRD, GABA(A) receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50.7 kD |
From 1,185.00€
*
Human GBRR1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120815.10
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]. Human...
| Keywords: | GABRR1, GABA(C) receptor, GABA(A) receptor subunit rho-1, Gamma-aminobutyric acid receptor subunit rho-1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 55.9 kD |
From 1,185.00€
*
Human GBRR3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120817.10
The neurotransmitter gamma-aminobutyric acid (GABA) functions in the central nervous system to regulate synaptic transmission of neurons. This gene encodes one of three related subunits, which combine as homo- or hetero-pentamers to form GABA(C) receptors. In humans, some individuals contain a single-base...
| Keywords: | GABRR3, GABA(C) receptor, GABA(A) receptor subunit rho-3, Gamma-aminobutyric acid receptor subunit rho-3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 54.3 kD |
From 1,185.00€
*
Human GLRA1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120819.10
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript...
| Keywords: | GLRA1, Glycine receptor 48 kDa subunit, Glycine receptor subunit alpha-1, Glycine receptor strychnine-binding subunit |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 52.6 kD |
From 1,185.00€
*
Human GLRB-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120822.10
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this...
| Keywords: | GLRB, Glycine receptor subunit beta, Glycine receptor 58 kDa subunit |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 56.1 kD |
From 1,185.00€
*
Human P2RX1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120823.10
The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates...
| Keywords: | P2X1, P2RX1, ATP receptor, P2X purinoceptor 1, Purinergic receptor |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 45 kD |
From 1,185.00€
*
Human P2RX2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120824.10
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene....
| Keywords: | P2X2, P2RX2, ATP receptor, P2X purinoceptor 2, Purinergic receptor |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51.8 kD |
From 1,185.00€
*
Human P2RX3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120825.10
This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein...
| Keywords: | P2X3, P2RX3, ATP receptor, P2X purinoceptor 3, Purinergic receptor |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 44.3 kD |
From 1,185.00€
*
Human GRID2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120830.10
The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the...
| Keywords: | GluD2, GRID2, GLURD2, GluR delta-2 subunit, Glutamate receptor ionotropic, delta-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 113.4 kD |
From 1,185.00€
*
Human GRIK4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120831.10
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional...
| Keywords: | KA1, GRIK, EAA1, GluK4, GRIK4, Glutamate receptor KA-1, Excitatory amino acid receptor 1, Glutamate receptor ionotropic,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 107.2 kD |
From 1,185.00€
*