Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human TRPV3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120776.10
This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct...
| Keywords: | TrpV3, TRPV3, VRL-3, Vanilloid receptor-like 3, Transient receptor potential cation channel subfamily V member 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 90.6 kD |
From 1,185.00€
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Human 5HT3A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120779.10
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in...
| Keywords: | 5HT3R, HTR3A, 5-HT-3, 5-HT3R, 5-HT3A, 5-HT3-A, Serotonin receptor 3A, 5-hydroxytryptamine receptor 3, 5-hydroxytryptamine... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 55.3 kD |
From 1,185.00€
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Human ACHA-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120784.10
The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have...
| Keywords: | ACHRA, CHRNA1, Acetylcholine receptor subunit alpha |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 54.5 kD |
From 1,185.00€
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Human ACHA2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120785.10
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic...
| Keywords: | CHRNA2, Neuronal acetylcholine receptor subunit alpha-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 59.8 kD |
From 1,185.00€
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Human ACHA3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120786.10
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a...
| Keywords: | CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 57.5 kD |
From 1,185.00€
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Human ACHA6-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120789.10
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are...
| Keywords: | CHRNA6, Neuronal acetylcholine receptor subunit alpha-6 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 56.9 kD |
From 1,185.00€
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Human ACHB-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120793.10
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting...
| Keywords: | ACHRB, CHRNB1, Acetylcholine receptor subunit beta |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 56.7 kD |
From 1,185.00€
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Human ACHB3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120795.10
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes...
| Keywords: | CHRNB3, Neuronal acetylcholine receptor subunit beta-3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 52.7 kD |
From 1,185.00€
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Human ACHD-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120797.10
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane....
| Keywords: | ACHRD, CHRND, Acetylcholine receptor subunit delta |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 58.9 kD |
From 1,185.00€
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Human ACHE-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120798.10
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit...
| Keywords: | CHRNE, ACHRE, Acetylcholine receptor subunit epsilon |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 54.7 kD |
From 1,185.00€
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Human GBRA1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120800.10
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the...
| Keywords: | GABRA1, GABA(A) receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51.8 kD |
From 1,185.00€
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Human GBRA2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120801.10
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A...
| Keywords: | GABRA2, GABA(A) receptor subunit alpha-2, Gamma-aminobutyric acid receptor subunit alpha-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51.3 kD |
From 1,185.00€
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