Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human CAC1D-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120737.10
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta,...
| Keywords: | CACH3, CACNA1D, Voltage-gated calcium channel subunit alpha Cav1.3, Calcium channel, L type, alpha-1 polypeptide, isoform... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 245.1 kD |
From 1,185.00€
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Human CAC1F-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120738.10
This gene encodes a multipass transmembrane protein that functions as an alpha-1 subunit of the voltage-dependent calcium channel, which mediates the influx of calcium ions into the cell. The encoded protein forms a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Mutations in this...
| Keywords: | CACNAF1, Voltage-gated calcium channel subunit alpha Cav1.4, Voltage-dependent L-type calcium channel subunit alpha-1F |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 220.7 kD |
From 1,185.00€
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Human CAC1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120744.10
This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation...
| Keywords: | CACNA1I, KIAA1120, Ca(v)3.3, Voltage-gated calcium channel subunit alpha Cav3.3, Voltage-dependent T-type calcium channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 245.1 kD |
From 1,185.00€
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Human CNGA1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120745.10
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause...
| Keywords: | CNCG, CNG1, CNG-1, CNGA1, CNG channel alpha-1, cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated channel alpha-1,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 79.6 kD |
From 1,185.00€
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Human CNGB1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120749.10
In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta...
| Keywords: | GARP, CNG4, CNGB1, CNCG2, CNG-4, CNG channel 4, CNG channel beta-1, Glutamic acid-rich protein, Cyclic nucleotide-gated... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 139.7 kD |
From 1,185.00€
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Human TRPC4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120757.10
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability,...
| Keywords: | hTrp4, TrpC4, TRPC4, hTrp-4, Trp-related protein 4, Short transient receptor potential channel 4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 112.1 kD |
From 1,185.00€
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Human TRPM3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120763.10
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion....
| Keywords: | TRPM3, MLSN2, LTrpC3, LTrpC-3, KIAA1616, Melastatin-2, Long transient receptor potential channel 3, Transient receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 197.6 kD |
From 1,185.00€
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Human TRPM8-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120768.10
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations...
| Keywords: | TRPM8, LTRPC6, Trp-p8, LTrpC6, LTrpC-6, Transient receptor potential p8, Long transient receptor potential channel 6,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 127.7 kD |
From 1,185.00€
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Human MCLN2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120770.10
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins...
| Keywords: | MCOLN2, TRPML2, Mucolipin-2, Transient receptor potential channel mucolipin 2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 65.9 kD |
From 1,185.00€
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Human MCLN3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120771.10
This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms...
| Keywords: | MCOLN3, TRPML3, Mucolipin-3, Transient receptor potential channel mucolipin 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 64.2 kD |
From 1,185.00€
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Human PKD2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120772.10
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be...
| Keywords: | PC2, R48321, Polycystwin, Polycystin-2, Polycystic kidney disease 2 protein, Autosomal dominant polycystic kidney disease... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 109.7 kD |
From 1,185.00€
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Human PK2L2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120774.10
May function as a subunit of a cation channel and play a role in fertilization.[UniProtKB/Swiss-Prot Function]. Human PK2L2-Strep full length protein-synthetic nanodisc. Protein function: May function as a subunit of a cation channel and play a role in fertilization. [The UniProt Consortium]
| Keywords: | PKD2L2, Polycystin-L2, Polycystin-2L2, Polycystic kidney disease 2-like 2 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 73.8 kD |
From 1,185.00€
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