Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human KCTD7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120714.10
This gene encodes a member of the potassium channel tetramerization domain-containing protein family. Family members are identified on a structural basis and contain an amino-terminal domain similar to the T1 domain present in the voltage-gated potassium channel. Mutations in this gene have been associated with...
| Keywords: | KCTD7, BTB/POZ domain-containing protein KCTD7 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 33.1 kD |
From 1,185.00€
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Human KCTD6-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120716.10
Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of...
| Keywords: | KCTD6, KCASH3 protein, BTB/POZ domain-containing protein KCTD6, Potassium channel tetramerization domain-containing protein 6 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 27.6 kD |
From 1,185.00€
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Human BACD1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120718.10
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates...
| Keywords: | KCTD13, FKSG86, hBACURD1, TNFAIP1-like protein, Polymerase delta-interacting protein 1, BTB/POZ domain-containing protein... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 36.4 kD |
From 1,185.00€
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Human KCTD1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120720.10
This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation...
| Keywords: | KCTD1, C18orf5, BTB/POZ domain-containing protein KCTD1, Potassium channel tetramerization domain-containing protein 1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 29.4 kD |
From 1,185.00€
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Human ZACN-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120721.10
LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels (Davies et al., 2003 [PubMed 12381728]).[supplied by OMIM, Mar 2008]. Human ZACN-Strep full length protein-synthetic nanodisc. Protein function: Zinc-activated ligand-gated...
| Keywords: | L2, ZACN, Ligand-gated ion-channel receptor L2, Zinc-activated ligand-gated ion channel, Ligand-gated ion channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 45.8 kD |
From 1,185.00€
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Human NMDE1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120722.10
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic...
| Keywords: | NR2A, hNR2A, GRIN2A, GluN2A, NMDAR2A, Glutamate receptor ionotropic, NMDA 2A, N-methyl D-aspartate receptor subtype 2A,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 165.3 kD |
From 1,185.00€
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Human SCN3A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120724.10
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the...
| Keywords: | SCN3A, KIAA1356, Voltage-gated sodium channel subtype III, Sodium channel protein type 3 subunit alpha, Sodium channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 226.3 kD |
From 1,185.00€
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Human SCN4A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120725.10
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the...
| Keywords: | SkM1, SCN4A, Sodium channel protein type 4 subunit alpha, Sodium channel protein type IV subunit alpha, Voltage-gated... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 208.1 kD |
From 1,185.00€
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Human SCN5A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120726.10
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT...
| Keywords: | hH1, SCN5A, Sodium channel protein type V subunit alpha, Sodium channel protein type 5 subunit alpha, Voltage-gated sodium... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 226.9 kD |
From 1,185.00€
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Human SCNAA-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120729.10
The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral...
| Keywords: | PN3, hPN3, SCN10A, Peripheral nerve sodium channel 3, Sodium channel protein type X subunit alpha, Sodium channel protein... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 220.6 kD |
From 1,185.00€
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Human SCNBA-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120730.10
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the...
| Keywords: | PN5, hNaN, SCN12A, SCN11A, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5, Sodium channel protein type... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 204.9 kD |
From 1,185.00€
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Human SCN3B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120733.10
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene...
| Keywords: | SCN3B, KIAA1158, Sodium channel subunit beta-3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 24.7 kD |
From 1,185.00€
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