Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human SCNNB-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120643.10
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with...
| Keywords: | SCNEB, ENaCB, SCNN1B, Beta-NaCH, Beta-ENaC, Epithelial Na(+) channel subunit beta, Nonvoltage-gated sodium channel 1... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 72.7 kD |
From 1,185.00€
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Human SCNNG-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120645.10
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle...
| Keywords: | SCNEG, ENaCG, SCNN1G, Gamma-NaCH, Gamma-ENaC, Epithelial Na(+) channel subunit gamma, Nonvoltage-gated sodium channel 1... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 74.3 kD |
From 1,185.00€
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Human BACD2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120646.10
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008]. Human...
| Keywords: | TNFAIP1, BACURD2, hBACURD2, Protein B12, BTB/POZ domain-containing protein TNFAIP1, Tumor necrosis factor, alpha-induced... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 36.2 kD |
From 1,185.00€
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Human VDAC2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120648.10
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of...
| Keywords: | VDAC2, VDAC-2, hVDAC2, Outer mitochondrial membrane protein porin 2, Voltage-dependent anion-selective channel protein 2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 31.6 kD |
From 1,185.00€
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Human VDAC3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120649.10
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought...
| Keywords: | VDAC3, VDAC-3, hVDAC3, Outer mitochondrial membrane protein porin 3, Voltage-dependent anion-selective channel protein 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 30.7 kD |
From 1,185.00€
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Human BEST1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120650.10
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally...
| Keywords: | VMD2, TU15B, BEST1, Bestrophin-1, Vitelliform macular dystrophy protein 2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 67.7 kD |
From 1,185.00€
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Human KCAB1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120651.10
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction,...
| Keywords: | KCNA1B, KCNAB1, Kv-beta-1, K(+) channel subunit beta-1, Voltage-gated potassium channel subunit beta-1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 46.6 kD |
From 1,185.00€
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Human CLIC3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120653.10
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is...
| Keywords: | CLIC3, Chloride intracellular channel protein 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 26.6 kD |
From 1,185.00€
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Human CA2D2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120655.10
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The...
| Keywords: | CACNA2D2, KIAA0558 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 129.8 kD |
From 1,185.00€
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Human ASIC3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120656.10
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with...
| Keywords: | ACCN3, ASIC3, hTNaC1, hASIC3, Testis sodium channel 1, Acid-sensing ion channel 3, Amiloride-sensitive cation channel 3,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 58.9 kD |
From 1,185.00€
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Human KCNE3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120658.10
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth...
| Keywords: | KCNE3, MinK-related peptide 2, Potassium channel subunit beta MiRP2, Minimum potassium ion channel-related peptide 2,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 11.7 kD |
From 1,185.00€
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Human TOM40-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120664.10
The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been...
| Keywords: | p38.5, TOMM40, C19orf1, Protein Haymaker, Mitochondrial import receptor subunit TOM40 homolog, Translocase of outer... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 37.9 kD |
From 1,185.00€
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