Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human CAC1E-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120741.10
Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or...
| Keywords: | BII, CACH6, CACNA1E, Brain calcium channel II, Voltage-gated calcium channel subunit alpha Cav2.3, Calcium channel, L... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 261.7 kD |
From 1,185.00€
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Human CAC1G-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120742.10
Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type,...
| Keywords: | NBR13, Cav3.1c, CACNA1G, KIAA1123, Voltage-gated calcium channel subunit alpha Cav3.1, Voltage-dependent T-type calcium... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 262.5 kD |
From 1,185.00€
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Human CNGA2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120746.10
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010]. Human CNGA2-Strep full length protein-synthetic nanodisc. Protein function:...
| Keywords: | CNCA, CNG2, CNG-2, CNGA2, CNG channel alpha-2, Cyclic nucleotide-gated channel alpha-2, Cyclic nucleotide-gated cation... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 76 kD |
From 1,185.00€
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Human TRPC1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120755.10
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular...
| Keywords: | TRP1, TRPC1, TrpC1, TRP-1, Transient receptor protein 1, Short transient receptor potential channel 1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 91.2 kD |
From 1,185.00€
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Human TRPM7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120767.10
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and...
| Keywords: | TRPM7, CHAK1, LTrpC7, LTrpC-7, EC=2.7.11.1, Channel-kinase 1, Long transient receptor potential channel 7, Transient... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 212.7 kD |
From 1,185.00€
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Human 5HT3D-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120782.10
The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric...
| Keywords: | HTR3D, 5-HT3D, 5-HT3-D, Serotonin receptor 3D, 5-hydroxytryptamine receptor 3D |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50.2 kD |
From 1,185.00€
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Human CXA1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120629.10
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the...
| Keywords: | GJA1, Cx43, GJAL, Connexin-43, Gap junction alpha-1 protein, Gap junction 43 kDa heart protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 43 kD |
From 1,185.00€
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Human CXA3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120630.10
The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010]. Human CXA3-Strep full length protein-synthetic nanodisc. Protein function: Structural component of lens fiber...
| Keywords: | Cx46, GJA3, Connexin-46, Gap junction alpha-3 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 47.4 kD |
From 1,185.00€
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Human CXB1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120633.10
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the...
| Keywords: | Cx32, CX32, GJB1, Connexin-32, Gap junction beta-1 protein, GAP junction 28 kDa liver protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 32 kD |
From 1,185.00€
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Human CXB5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120636.10
This gene encodes a member of the beta-type (group I) connexin family. The encoded protein is a gap junction protein involved in intercellular communication related to epidermal differentiation and environmental sensing. This gene has been linked to non-small cell lung cancer. [provided by RefSeq, Nov 2012]. Human...
| Keywords: | GJB5, Cx31.1, Connexin-31.1, Gap junction beta-5 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 31.1 kD |
From 1,185.00€
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Human SCN7A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120641.10
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics, the similarity between...
| Keywords: | SCN7A, SCN6A, Sodium channel protein type 7 subunit alpha, Sodium channel protein type VII subunit alpha, Putative... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 193.5 kD |
From 1,185.00€
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Human SCNNA-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120642.10
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with...
| Keywords: | SCNEA, ENaCA, SCNN1, SCNN1A, Alpha-ENaC, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Nonvoltage-gated sodium... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 75.7 kD |
From 1,185.00€
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