Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human FXYD6-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120684.10
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on...
| Keywords: | FXYD6, Phosphohippolin, FXYD domain-containing ion transport regulator 6 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 10.5 kD |
From 1,185.00€
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Human KCTD5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120687.10
Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (PubMed:18573101). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (PubMed:19361449).[UniProtKB/Swiss-Prot Function]. Human KCTD5-Strep full length protein-synthetic...
| Keywords: | KCTD5, BTB/POZ domain-containing protein KCTD5 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 26.1 kD |
From 1,185.00€
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Human TTYH1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120691.10
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2 )-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for...
| Keywords: | hTTY1, TTYH1, Protein tweety homolog 1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 49.1 kD |
From 1,185.00€
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Human CCG7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120693.10
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two...
| Keywords: | CACNG7, TARP gamma-7, Transmembrane AMPAR regulatory protein gamma-7, Voltage-dependent calcium channel gamma-7 subunit,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 31 kD |
From 1,185.00€
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Human KCD14-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120695.10
. Human KCD14-Strep full length protein-synthetic nanodisc.
| Keywords: | KCTD14, BTB/POZ domain-containing protein KCTD14 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 29.6 kD |
From 1,185.00€
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Human KCD17-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120698.10
This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a...
| Keywords: | KCTD17, BTB/POZ domain-containing protein KCTD17 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 35.7 kD |
From 1,185.00€
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Human CRFM7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120705.10
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a...
| Keywords: | D-10, CHRFAM7A, CHRNA7-DR1, CHRNA7-FAM7A fusion protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 46.2 kD |
From 1,185.00€
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Human KCD20-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120717.10
Promotes the phosphorylation of AKT family members.[UniProtKB/Swiss-Prot Function]. Human KCD20-Strep full length protein-synthetic nanodisc. Protein function: Promotes the phosphorylation of AKT family members. [The UniProt Consortium]
| Keywords: | KCTD20, C6orf69, BTB/POZ domain-containing protein KCTD20, Potassium channel tetramerization domain containing 20 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 47.5 kD |
From 1,185.00€
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Human SCN2A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120723.10
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action...
| Keywords: | NAC2, SCN2A, HBSC II, Sodium channel protein type 2 subunit alpha, Sodium channel protein type II subunit alpha, Sodium... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 228 kD |
From 1,185.00€
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Human SCN9A-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120728.10
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]. Human SCN9A-Strep...
| Keywords: | PN1, NENA, hNE-Na, Peripheral sodium channel 1, Neuroendocrine sodium channel, Sodium channel protein type 9 subunit... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 226.4 kD |
From 1,185.00€
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Human CAC1S-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120735.10
This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul...
| Keywords: | CACNA1S, Voltage-gated calcium channel subunit alpha Cav1.1, Voltage-dependent L-type calcium channel subunit alpha-1S,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 212.4 kD |
From 1,185.00€
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Human CAC1B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120740.10
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to...
| Keywords: | BIII, CACH5, CACNA1B, Brain calcium channel III, Voltage-gated calcium channel subunit alpha Cav2.2, Calcium channel, L... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 262.5 kD |
From 1,185.00€
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