Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human KCMB1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120638.10
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit....
| Keywords: | KCNMB1, Hbeta1, BKbeta, BKbeta1, Slo-beta, Slo-beta-1, K(VCA)beta-1, BK channel subunit beta-1, Maxi K channel subunit... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 21.8 kD |
From 1,185.00€
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Human PLM-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120639.10
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport...
| Keywords: | Phospholemman, FXYD domain-containing ion transport regulator 1, Sodium/potassium-transporting ATPase subunit FXYD1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 10.4 kD |
From 1,185.00€
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Human SCNND-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120644.10
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a...
| Keywords: | SCNED, DNACH, ENaCD, SCNN1D, Delta-NaCH, Delta-ENaC, Epithelial Na(+) channel subunit delta, Nonvoltage-gated sodium... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 87.9 kD |
From 1,185.00€
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Human VDAC1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120647.10
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the...
| Keywords: | VDAC, VDAC1, hVDAC1, VDAC-1, Porin 31HM, Porin 31HL, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 30.8 kD |
From 1,185.00€
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Human KCAB2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120652.10
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth...
| Keywords: | KCNAB2, KCNA2B, hKvbeta2, Kv-beta-2, K(+) channel subunit beta-2, Voltage-gated potassium channel subunit beta-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 41 kD |
From 1,185.00€
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Human CXG1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120659.10
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same...
| Keywords: | Cx45, GJA7, GJC1, Connexin-45, Gap junction gamma-1 protein, Gap junction alpha-7 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 45.5 kD |
From 1,185.00€
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Human KCMB2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120660.10
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is...
| Keywords: | Hbeta2, KCNMB2, Hbeta3, BKbeta2, Slo-beta-2, K(VCA)beta-2, BK channel subunit beta-2, Maxi K channel subunit beta-2,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 27.1 kD |
From 1,185.00€
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Human CCG2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120663.10
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. The AMPA subtype of ionotropic glutamate receptors are ligand gated ion channels that are typically activated by glutamate released from...
| Keywords: | CACNG2, TARP gamma-2, Transmembrane AMPAR regulatory protein gamma-2, Voltage-dependent calcium channel gamma-2 subunit,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 36 kD |
From 1,185.00€
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Human CLCA4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120665.10
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue...
| Keywords: | CLCA4, CaCC2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 101.3 kD |
From 1,185.00€
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Human CLCC1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120666.10
Seems to act as a chloride ion channel.[UniProtKB/Swiss-Prot Function]. Human CLCC1-Strep full length protein-synthetic nanodisc. Protein function: Seems to act as a chloride ion channel (PubMed:30157172). Plays a role in retina development (PubMed:30157172). [The UniProt Consortium]
| Keywords: | CLCC1, KIAA0761, Chloride channel CLIC-like protein 1, Mid-1-related chloride channel protein 1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 62 kD |
From 1,185.00€
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Human KCNE5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120668.10
This gene encodes a member of a family of single pass transmembrane domain proteins that function as ancillary subunits to voltage-gated potassium channels. Members of this family affect diverse processes in potassium channel regulation, including ion selectivity, voltage dependence, and anterograde recycling from...
| Keywords: | KCNE5, AMMECR2, Potassium channel subunit beta MiRP4, AMME syndrome candidate gene 2 protein, Potassium voltage-gated... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 15 kD |
From 1,185.00€
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Human CLIC5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120682.10
This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and...
| Keywords: | CLIC5, Chloride intracellular channel protein 5 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 46.5 kD |
From 1,185.00€
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