Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human CD27 Protein, mFc-His Tag
Item number: DIM-PME100013.10
Recombinant human CD27 protein with C-terminal mouse Fc and 6×His tag. CD27(Ala20-Arg191) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Keywords: | CD27, TNFRSF7, S152, T14, Tp55 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 65-72 kD |
From 140.00€
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Human CD40 Protein, mFc-His Tag
Item number: DIM-PME100015.10
Recombinant human CD40 protein with C-terminal mouse Fc and 6×His tag. CD40(Glu21-Arg193) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin...
| Keywords: | CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 68 kD |
From 120.00€
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Human CD48 Protein, mFc-His Tag
Item number: DIM-PME100016.10
Recombinant human CD48 protein with C-terminal mouse Fc and 6×His. CD48(Gln27-Ser220) mFc(Pro99-Lys330) 6×His, Protein function: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [The UniProt Consortium]
| Keywords: | CD48, BCM1, SLAMF2, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 69-72 kD |
From 133.00€
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Human CTLA-4 Protein, mFc-His Tag
Item number: DIM-PME100017.10
Recombinant human CTLA-4 protein with C-terminal mouse Fc and 6×His tag. CTLA-4(Lys36-Asp161) mFc(Pro99-Lys330) 6×His tag, Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger...
| Keywords: | CTLA4, CD152 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 54 kD |
From 140.00€
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Human GITR Protein, hFc-His tag
Item number: DIM-PME100018.10
Recombinant human GITR protein with C-terminal human Fc and 6×His tag. GITR(Gln26-Pro162) hFc(Glu99-Ala330) 6×His, Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated...
| Keywords: | AITR, GITR, TNFRSF18, CD357 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51-52 kD |
From 140.00€
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Human GITR Protein, mFc-His tag
Item number: DIM-PME100019.10
Recombinant human GITR protein with C-terminal mouse Fc and 6×His tag. GITR(Gln26-Pro162) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated...
| Keywords: | AITR, GITR, TNFRSF18, CD357 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50-52 kD |
From 114.00€
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Human GITR Ligand Protein, mFc-His tag
Item number: DIM-PME100020.10
Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) GITR Ligand(Gln50-Ser177) 6×His, Protein function: Cytokine that binds to TNFRSF18/AITR/GITR (PubMed:14521928, PubMed:14647196). Regulates T-cell responses (PubMed:14647196). Can function as costimulator and...
| Keywords: | TNFSF18, AITRL, TL6, hGITRL, GITR Ligand |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 46-53 kD |
From 124.00€
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Human OX40L Protein, mFc-His tag
Item number: DIM-PME100021.10
Recombinant human OX40L protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) OX40 Ligand(Gln51-Leu183) 6×His, Protein function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. [The UniProt Consortium]
| Keywords: | OX40L, TNFSF4, CD252, Glycoprotein Gp34, TXGP1, CD134 ligand, CD134L |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 44.0 kD |
From 140.00€
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Human OX40 Protein, hFc-His tag
Item number: DIM-PME100022.10
Recombinant human OX40 protein with C-terminal human Fc and 6×His tag. OX40(Leu29-Ala214) hFc(Glu99-Ala330) 6×His tag, Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
| Keywords: | TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 47.2 kD |
From 140.00€
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Human SLAMF1 Protein, mFc-His tag
Item number: DIM-PME100024.10
Recombinant human SLAMF1 protein with C-terminal mouse Fc and 6×His tag. SLAMF1(Ala21-Pro237) mFc(Pro99-Lys330) 6×His tag, Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the...
| Keywords: | SLAMF1, CD150, CDw150, SLAM, IPO-3 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51.8 kD |
From 140.00€
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Human PD-1 Protein, mFc-His tag
Item number: DIM-PME100025.10
Recombinant human PD-1 protein with C-terminal mouse Fc and 6×His tag. PD-1(Phe24-Val170) mFc(Pro99-Lys330) 6×His tag, Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals...
| Keywords: | PDCD1, PD1, CD279, SLEB2 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 43.5 kD |
From 140.00€
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Human ICOS Protein, mFc-His tag
Item number: DIM-PME100026.10
Recombinant human ICOS protein with C-terminal mouse Fc and 6×His tag. ICOS(Glu21-Lys140) mFc(Pro99-Lys330) 6×His tag, Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and...
| Keywords: | ICOS, CD278, AILIM, Inducible T-cell costimulator |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 41.1 kD |
From 133.00€
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