Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Biotinylated Anti-OX40( ivuxolimab biosimilar)mAb
Item number: DIM-BME100053B.100
Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
| Keywords: | Anti-TNFRSF4, Anti-OX40, Anti-CD134, Anti-OX40L receptor, Anti-ACT35, Anti-TXGP1L, Biotinylated Anti-OX40( ivuxolimab... |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-BTLA (icatolimab biosimilar)mAb
Item number: DIM-BME100054B.100
Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis...
| Keywords: | Anti-BTLA, Anti-CD272, Biotinylated Anti-BTLA (icatolimab biosimilar)mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CSF1R(cabiralizumab biosimilar) mAb
Item number: DIM-BME100055B.100
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Keywords: | Anti-CSF1R, Anti-C-FMS, Anti-CD115, Anti-CSFR, Anti-FIM2, Anti-FMS, Anti-M-CSFR, Biotinylated Anti-CSF1R(cabiralizumab... |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-TNFa(Adalimumab biosimilar) mAb
Item number: DIM-BME100056B.100
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,...
| Keywords: | Anti-DIF, Anti-TNF-alpha, Anti-TNFA, Anti-TNFSF2, Anti-cachexin, Anti-cachectin, Anti-TNFalpha, Biotinylated... |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-HER3 (patritumab biosimilar)mAb
Item number: DIM-BME100057B.100
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase...
| Keywords: | Anti-HER3, Anti-ERBB3, Biotinylated Anti-HER3 (patritumab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-TNFSF11 (denosumab biosimilar)mAb
Item number: DIM-BME100058B.100
Protein function: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the...
| Keywords: | Anti-CD254, Anti-hRANKL2, Anti-ODF, Anti-OPGL, Anti-OPTB2, Anti-RANKL, Anti-sOdf, Anti-TNLG6B, Anti-TRANCE, Biotinylated... |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-MUC1(gatipotuzumab biosimilar) mAb
Item number: DIM-BME100059B.100
Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
| Keywords: | Anti-ADMCKD, Anti-ADMCKD1, Anti-CA 15-3, Anti-CD227, Anti-EMA, Anti-H23AG, Anti-KL-6, Anti-MAM6, Anti-MCD, Anti-MCKD,... |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-VEGFR2 (ramucirumab biosimilar)mAb
Item number: DIM-BME100060B.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of...
| Keywords: | Anti-CD309, Anti-FLK1, Anti-VEGFR, Anti-VEGFR2, Biotinylated Anti-VEGFR2 (ramucirumab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-VEGFA(bevacizumab biosimiar) mAb
Item number: DIM-BME100061B.100
Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin....
| Keywords: | Anti-rhuMAb-VEGF, Biotinylated Anti-VEGFA(bevacizumab biosimiar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-LAG3 (relatlimab biosimilar)mAb
Item number: DIM-BME100062B.100
Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory...
| Keywords: | Anti-BMS-986016, Anti-ONO-4482, Biotinylated Anti-LAG3 (relatlimab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CCR8(10A11) mAb
Item number: DIM-BME100063B.100
Protein function: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. [The UniProt Consortium]
| Keywords: | Anti-CC-CKR-8, Anti-CCR-8, Anti-CDw198, Anti-CKRL1, Anti-CMKBR8, Anti-CMKBRL2, Anti-CY6, Anti-GPRCY6, Anti-TER1,... |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-ADAM9 (biosimilar) mAb
Item number: DIM-BME100064B.100
Protein function: Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. [The UniProt Consortium]
| Keywords: | Anti-CORD9, Anti-MCMP, Anti-MDC9, Anti-Mltng, Biotinylated Anti-ADAM9 (biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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