Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Biotinylated Anti-IL17RA (brodalumab biosimilar) mAb
Item number: DIM-BME100038B.100
Protein function: Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A (PubMed:17911633, PubMed:9367539). Receptor for IL17F (PubMed:19838198, PubMed:17911633). Binds to IL17A with...
| Keywords: | Anti-CD217, Anti-CDw217, Anti-IL-17RA, Anti-IL17R, Anti-CANDF5, Anti-hIL-17R, Biotinylated Anti-IL17RA (brodalumab... |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-NKG2D (tesnatilimab biosimilar) mAb
Item number: DIM-BME100039B.100
Protein function: Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on...
| Keywords: | Anti-NKG2D, Anti-CD314, Anti-KLRK1, Anti-NK cell receptor D, Biotinylated Anti-NKG2D (tesnatilimab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CA9 (girentuximab biosimilar) mAb
Item number: DIM-BME100040B.100
Protein function: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. [The UniProt Consortium]
| Keywords: | Anti-CAIX, Anti-MN, Biotinylated Anti-CA9 (girentuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-IL6R (tocilizumab biosimilar) mAb
Item number: DIM-BME100041B.100
Protein function: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis (Probable). The...
| Keywords: | Anti-CD126, Anti-gp80, Anti-IL-6R-1, Anti-IL-6RA, Anti-IL6Q, Anti-IL6RA, Anti-IL6RQ, Biotinylated Anti-IL6R (tocilizumab... |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD40 Ligand (ruplizumab biosimilar) mAb
Item number: DIM-BME100042B.100
Protein function: Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3...
| Keywords: | Anti-CD40LG, Anti-CD154, Anti-CD40L, Anti-HIGM1, Anti-IGM, Anti-IMD3, Anti-T-BAM, Anti-TNFSF5, Anti-TRAP, Anti-gp39,... |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-IL2RA (basiliximab biosimilar) mAb
Item number: DIM-BME100043B.100
Protein function: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [The UniProt Consortium]
| Keywords: | Anti-IL2RA, Anti-CD25, Anti-p55, Anti-IL2-RA, Anti-IL-2-RA, Biotinylated Anti-IL2RA (basiliximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-BAFF (belimumab biosimilar) mAb
Item number: DIM-BME100044B.100
Protein function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3)...
| Keywords: | Anti-TNFSF13B, Anti-BAFF, Anti-BLYS, Anti-CD257, Anti-DTL, Anti-TALL1, Anti-THANK, Anti-TNFSF20, Anti-ZTNF4, Anti-TALL-1,... |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-BAFFR (ianalumab biosimilar) mAb
Item number: DIM-BME100045B.100
Protein function: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. [The UniProt Consortium]
| Keywords: | Anti-BAFFR, Anti-TNFRSF13C, Anti-BAFF-R, Anti-BROMIX, Anti-CD268, Anti-CVID4, Anti-prolixin, Biotinylated Anti-BAFFR... |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD37 (naratuximab biosimilar) mAb
Item number: DIM-BME100046B.100
| Keywords: | Anti-CD37, Anti-TSPAN26, Anti-Tspan-26, Biotinylated Anti-CD37 (naratuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD47 (magrolimab biosimilar,IgG1) mAb
Item number: DIM-BME100050B.100
Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells...
| Keywords: | Anti-CD47, Anti-MER6, Anti-IAP, Biotinylated Anti-CD47 (magrolimab biosimilar,IgG1) mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD19 (inebilizumab biosimilar)mAb
Item number: DIM-BME100051B.100
Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead...
| Keywords: | Anti-CD19, Anti-4, Anti-VID3, Anti-GC12802, Biotinylated Anti-CD19 (inebilizumab biosimilar)mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-IL-4RA (dupilumab biosimilar)mAb
Item number: DIM-BME100052B.100
Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In...
| Keywords: | Anti-CD124, Anti-IL-4RA, Anti-IL4RA, Biotinylated Anti-IL-4RA (dupilumab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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