Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Biotinylated Anti-CD33 (gemtuzumab biosimilar) mAb
Item number: DIM-BME100015B.100
Protein function: Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (PubMed:10611343, PubMed:15597323, PubMed:11320212). Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked...
| Keywords: | Anti-CD33, Anti-SIGLEC3, Anti-gp67, Biotinylated Anti-CD33 (gemtuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-BCMA (biosimilar) mAb
Item number: DIM-BME100016B.100
Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Keywords: | Anti-CD269, Anti-TNFRSF17, Anti-BCM, Anti-BCMA, Biotinylated Anti-BCMA (biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD30 (brentuximab biosimilar) mAb
Item number: DIM-BME100017B.100
Protein function: Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa- B (PubMed:8999898). [The UniProt Consortium]
| Keywords: | Anti-TNFRSF8, Anti-CD30, Anti-D1S166E, Anti-Ki-1, Biotinylated Anti-CD30 (brentuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD27 (varlilumab biosimilar) mAb
Item number: DIM-BME100018B.100
Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Keywords: | Anti-CD27, Anti-TNFRSF7, Anti-S152, Anti-T14, Anti-Tp55, Biotinylated Anti-CD27 (varlilumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-EPHA3 (ifabotuzumab biosimilar) mAb
Item number: DIM-BME100019B.100
Protein function: Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling...
| Keywords: | Anti-TYRO4, Anti-HEK4, Anti-ETK1, Anti-ETK, Anti-EK4, Anti-HEK, Biotinylated Anti-EPHA3 (ifabotuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD40 (iscalimab biosimilar) mAb
Item number: DIM-BME100020B.100
Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | Anti-CD40, Anti-Bp50, Anti-CDW40, Anti-MGC9013, Anti-TNFRSF5, Anti-p50, Biotinylated Anti-CD40 (iscalimab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-Mesothelin (amatuximab biosimilar) mAb
Item number: DIM-BME100021B.100
Protein function: Membrane-anchored forms may play a role in cellular adhesion. [The UniProt Consortium]
| Keywords: | Anti-MSLN, Anti-Mesothelin, Anti-MPF, Biotinylated Anti-Mesothelin (amatuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CTLA-4 (ipilimumab biosimilar) mAb
Item number: DIM-BME100022B.100
Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | Anti-CTLA4, Anti-CD152, Biotinylated Anti-CTLA-4 (ipilimumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-Trop2 (sacituzumab biosimilar) mAb
Item number: DIM-BME100023B.100
Protein function: May function as a growth factor receptor. [The UniProt Consortium]
| Keywords: | Anti-TACSTD2, Anti-GA733-1, Anti-M1S1, Anti-TROP2, Biotinylated Anti-Trop2 (sacituzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-TIGIT (etigilimab biosimilar) mAb
Item number: DIM-BME100024B.100
Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | Anti-TIGIT, Anti-SIG9, Anti-STM3, Biotinylated Anti-TIGIT (etigilimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-CD20 (rituximab biosimilar) mAb
Item number: DIM-BME100025B.100
Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component...
| Keywords: | Anti-B1, Anti-Bp35, Anti-CD20, Anti-CVID5, Anti-LEU-16, Anti-MS4A2, Anti-S7, Biotinylated Anti-CD20 (rituximab biosimilar)... |
| Host: | Chimeric |
| Species reactivity: | human |
From 145.00€
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Biotinylated Anti-TIGIT (tiragolumab biosimilar) mAb
Item number: DIM-BME100026B.100
Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | Anti-TIGIT, Anti-SIG9, Anti-STM3, Biotinylated Anti-TIGIT (tiragolumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 145.00€
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