Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Biotinylated Anti-NKG2D antibody(DMC287), IgG1 Chimeric mAb
Item number: DIM-DMC100287B.10
Protein function: Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on...
| Keywords: | Anti-NKG2D, Anti-CD314, Anti-KLRK1, Anti-NK cell receptor D, Biotinylated Anti-NKG2D antibody(DMC287), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-CCR4 antibody(DMC297), IgG1 Chimeric mAb
Item number: DIM-DMC100297B.10
Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating...
| Keywords: | Anti-CC-CKR-4, Anti-CD194, Anti-ChemR13, Anti-CKR4, Anti-CMKBR4, Anti-HGCN:14099, Anti-K5-5, Biotinylated Anti-CCR4... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-NKG2A antibody(DMC298), IgG1 Chimeric mAb
Item number: DIM-DMC100298B.10
Protein function: Immune inhibitory receptor involved in self-nonself discrimination. In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class...
| Keywords: | Anti-CD159A, Anti-NKG2, Anti-NKG2A, Biotinylated Anti-NKG2A antibody(DMC298), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-B7-H5 antibody(DMC299), IgG1 Chimeric mAb
Item number: DIM-DMC100299B.10
Protein function: Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14- mediated MMP2 activation (PubMed:20666777). [The UniProt Consortium]
| Keywords: | Anti-B7-H5, Anti-B7H5, Anti-C10orf54, Anti-DD1alpha, Anti-Dies1, Anti-GI24, Anti-PD-1H, Anti-PP2135, Anti-SISP1,... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-CD93 antibody(5B10), IgG1 Chimeric mAb
Item number: DIM-DMC100345B.10
Protein function: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion....
| Keywords: | Anti-C1qR(P), Anti-C1QR1, Anti-C1qRP, Anti-CDw93, Anti-dJ737E23.1, Anti-ECSM3, Anti-MXRA4, Biotinylated Anti-CD93... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-CFB antibody(DMC366), IgG1 Chimeric mAb
Item number: DIM-DMC100366B.10
Protein function: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of...
| Keywords: | Anti-AHUS4, Anti-ARMD14, Anti-BF, Anti-BFD, Anti-CFAB, Anti-CFBD, Anti-FB, Anti-FBI12, Anti-GBG, Anti-H2-Bf, Anti-PBF2,... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-ICAM-1 antibody(DMC367), IgG1 Chimeric mAb
Item number: DIM-DMC100367B.10
Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. [The UniProt Consortium]
| Keywords: | Anti-ICAM1, Anti-BB2, Anti-CD54, Anti-P3.58, Biotinylated Anti-ICAM-1 antibody(DMC367), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-GPR75 antibody(DMC368), IgG1 Chimeric mAb
Item number: DIM-DMC100368B.10
Protein function: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a...
| Keywords: | Anti-Probable G-protein coupled receptor 75, Biotinylated Anti-GPR75 antibody(DMC368), IgG1 Chimeric mAb |
| Application: | FC |
| Host: | Rabbit/Human |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-HER2 antibody(DMC369), IgG1 Chimeric mAb
Item number: DIM-DMC100369B.10
Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor....
| Keywords: | Anti-ERBB2, Anti-CD340, Anti-HER-2:neu, Anti-HER2, Anti-MLN19, Anti-NEU, Anti-NGL, Anti-TKR1, Biotinylated Anti-HER2... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-ADGRE2 antibody(DMC370), IgG1 Chimeric mAb
Item number: DIM-DMC100370B.10
Protein function: Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through...
| Keywords: | Anti-Adhesion G protein-coupled receptor E2, Anti-EGF-like module receptor 2, Anti-EGF-like module-containing mucin-like... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-GPC3 antibody(DMC371), IgG1 Chimeric mAb
Item number: DIM-DMC100371B.10
Protein function: Cell surface proteoglycan that bears heparan sulfate (PubMed:14610063). Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH...
| Keywords: | Anti-DGSX, Anti-GTR2-2, Anti-MXR7, Anti-OCI-5, Anti-SDYS, Anti-SGB, Anti-SGBS, Anti-SGBS1, Biotinylated Anti-GPC3... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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Biotinylated Anti-CSF1R antibody(9A5), IgG1 Chimeric mAb
Item number: DIM-DMC100382B.10
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Keywords: | Anti-CSF1R, Anti-C-FMS, Anti-CD115, Anti-CSFR, Anti-FIM2, Anti-FMS, Anti-M-CSFR, Biotinylated Anti-CSF1R antibody(9A5),... |
| Host: | Rabbit |
| Species reactivity: | human |
From 203.00€
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