Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-FZD10(tabituximab biosimilar) mAb
Item number: DIM-BME100185.100
Protein function: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second...
| Keywords: | Anti-CD350, Anti-FZ-10, Anti-Fz10, Anti-FzE7, Anti-hFz10, Anti-FZD10(tabituximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-ALPP(SGN-ALPV biosimilar) mAb
Item number: DIM-BME100186.100
| Keywords: | Anti-PLAP, Anti-ALPP(SGN-ALPV biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GPRC5D(LM305 biosimilar) mAb
Item number: DIM-BME100187.100
| Keywords: | Anti-GPRC5D, Anti-GPRC5D(LM305 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-STEAP1(Vandortuzumab biosimilar) mAb
Item number: DIM-BME100188.100
Protein function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. [The UniProt Consortium]
| Keywords: | Anti-PRSS24, Anti-STEAP, Anti-STEAP1(Vandortuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-EPCAM(IMC001 biosimilar) mAb
Item number: DIM-BME100189.100
Protein function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells...
| Keywords: | Anti-GA733-2, Anti-M1S2, Anti-M4S1, Anti-MIC18, Anti-TACSTD1, Anti-TROP1, Anti-EPCAM(IMC001 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H4(AZD-8205 biosimilar) mAb
Item number: DIM-BME100190.100
Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in the suppression of...
| Keywords: | Anti-VTCN1, Anti-B7-H4(AZD-8205 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-ROR1(NBE 002 biosimilar) mAb
Item number: DIM-BME100191.100
Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear,...
| Keywords: | Anti-NTRKR1, Anti-ROR1(NBE 002 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H4(XMT-1660 biosimilar) mAb
Item number: DIM-BME100192.100
Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in the suppression of...
| Keywords: | Anti-VTCN1, Anti-B7-H4(XMT-1660 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GPRC5D(LBL-034 biosimilar) mAb
Item number: DIM-BME100193.100
| Keywords: | Anti-GPRC5D, Anti-GPRC5D(LBL-034 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GPNMB(glembatumumab biosimilar) mAb
Item number: DIM-BME100194.100
Protein function: Could be a melanogenic enzyme. [The UniProt Consortium]
| Keywords: | Anti-HGFIN, Anti-NMB, Anti-GPNMB(glembatumumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-CEACAM5(tusamitamab biosimilar) mAb
Item number: DIM-BME100195.100
Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6...
| Keywords: | Anti-CEA, Anti-CEACAM5(tusamitamab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-GPRC5D and CD3(LBL-034 biosimilar) BsAb
Item number: DIM-BME100196.100
| Keywords: | Anti-GPRC5D, Anti-CD3, Anti-GPRC5D and CD3(LBL-034 biosimilar) BsAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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