Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-IL5 (varokibart biosimilar) mAb
Item number: DIM-BME100720.100
Research use only. Protein function: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. [The UniProt Consortium]
| Keywords: | TEV-53275,TEV53275,TEV 53275, Anti-TRF, Anti-IL5, Anti-IL-5, Anti-Interleukin-5, Anti-T-cell replacing factor, Anti-B-cell... |
| Species reactivity: | human |
From 120.00€
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Anti-IGF-1R (veligrotug biosimilar) mAb
Item number: DIM-BME100721.100
Research use only. Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation...
| Keywords: | AVE-1642,AVE1642,AVE 1642,VRDN-001,VRDN001,VRDN 001,ZB 001,ZB-001,ZB001, Anti-IGF1R, EC=2.7.10.1 |
| Species reactivity: | human |
From 120.00€
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Anti-BTLA (venanprubart biosimilar) mAb
Item number: DIM-BME100722.100
Research use only. Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14...
| Keywords: | LY-3361237,LY3361237,LY 3361237, Anti-CD272, Anti-B- and T-lymphocyte attenuator, Anti-B- and T-lymphocyte-associated protein |
| Species reactivity: | human |
From 120.00€
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Anti-TIM3 (verzistobart biosimilar) mAb
Item number: DIM-BME100724.100
Research use only. Protein function: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand...
| Keywords: | INCAGN2390,INCAGN02390,INCAGN-2390,INCAGN-02390, Anti-TIM3, Anti-TIM-3, Anti-CD366, Anti-TIMD-3, Anti-HAVCR2,... |
| Species reactivity: | human |
From 120.00€
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Anti-CTLA-4 (vilastobart biosimilar) mAb, biotinylated
Item number: DIM-BME100726B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | XTX-101,XTX 101,XTX101, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 145.00€
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Anti-B7-H3 (vobramitamab biosimilar) mAb, biotinylated
Item number: DIM-BME100730B.100
Research use only. Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and...
| Keywords: | MGA017,MGA-017,MGA17,MGA-17,MGA 017,MGA 17,MGA018,MGA-018,MGA18,MGA-18,MGA 018,MGA 18,AEX4089,AEX-4089,AEX 4089,... |
| Species reactivity: | human |
From 145.00€
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Anti-IL17A (xeligekimab biosimilar) mAb
Item number: DIM-BME100733.100
Research use only. Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with...
| Keywords: | GR-1501,GR1501,GR 1501, Anti-IL-17, Anti-CTLA8, Anti-IL17A, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A, Anti-Cytotoxic... |
| Species reactivity: | human |
From 120.00€
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Anti-TGM2 (zampilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100736B.100
Research use only. Protein function: Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins. [The UniProt Consortium]
| Keywords: | UCB 7858,UCB-7858,UCB7858, Anti-TGC, Anti-TGM2, Anti-TG(C), Anti-TGase H, Anti-TGase C, Anti-TGase-2, EC=2.3.2.13,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (zeluvalimab biosimilar) mAb
Item number: DIM-BME100738.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | 20C1.009,AMG-404,AMG404,AMG 404, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-APRIL (zigakibart biosimilar) mAb
Item number: DIM-BME100739.100
Research use only. Protein function: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. [The UniProt Consortium]
| Keywords: | BION-1301,BION1301,BION 1301, Anti-APRIL, Anti-CD256, Anti-TALL-2, Anti-TRDL-1, Anti-TNFSF13, Anti-TNF-related death... |
| Species reactivity: | human |
From 120.00€
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Anti-IGHE (ligelizumab biosimilar) mAb
Item number: DIM-BME100553.100
Research use only. Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon...
| Keywords: | QGE-031,QGE031,QGE 031,QGE31,QGE-31,QGE 31, Anti-Ig epsilon chain C region, Anti-Ig epsilon chain C region ND,... |
| Species reactivity: | human |
From 120.00€
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Anti-IGHE (ligelizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100553B.100
Research use only. Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon...
| Keywords: | QGE-031,QGE031,QGE 031,QGE31,QGE-31,QGE 31, Anti-Ig epsilon chain C region, Anti-Ig epsilon chain C region ND,... |
| Species reactivity: | human |
From 145.00€
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