Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CEACAM6(tinurilimab biosimilar) mAb
Item number: DIM-BME100100.100
Protein function: Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:2803308, PubMed:2022629, PubMed:1378450, PubMed:8776764, PubMed:11590190, PubMed:10910050, PubMed:14724575, PubMed:16204051). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner...
| Keywords: | Anti-CD66c, Anti-CEAL, Anti-NCA, Anti-CEACAM6(tinurilimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CXCR4(ulocuplumab biosimilar) mAb
Item number: DIM-BME100101.100
Protein function: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:28978524, PubMed:18799424, PubMed:24912431). Involved in the AKT signaling cascade (PubMed:24912431). Plays a role in...
| Keywords: | Anti-CD184, Anti-D2S201E, Anti-FB22, Anti-HM89, Anti-HSY3RR, Anti-LAP-3, Anti-LAP3, Anti-LCR1, Anti-LESTR, Anti-NPY3R,... |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-CD56(lorvotuzumab biosimilar) mAb
Item number: DIM-BME100102.100
Protein function: This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [The UniProt Consortium]
| Keywords: | Anti-MSK39, Anti-NCAM, Anti-CD56(lorvotuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-IL21(avizakimab biosimilar) mAb
Item number: DIM-BME100103.100
Protein function: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6,...
| Keywords: | Anti-CVID11, Anti-Za11, Anti-IL21(avizakimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-M-CSF(lacnotuzumab biosimilar) mAb
Item number: DIM-BME100104.100
Protein function: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in...
| Keywords: | Anti-CSF-1, Anti-MCSF, Anti-M-CSF(lacnotuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CCN2(pamrevlumab biosimilar) mAb
Item number: DIM-BME100105.100
Protein function: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells....
| Keywords: | Anti-CTGF, Anti-HCS24, Anti-IGFBP8, Anti-NOV2, Anti-CCN2(pamrevlumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-AMHR2(murlentamab biosimilar) mAb
Item number: DIM-BME100106.100
Protein function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian...
| Keywords: | Anti-AMHR, Anti-MISR2, Anti-MISRII, Anti-MRII, Anti-AMHR2(murlentamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-DKK1(sirexatamab biosimilar) mAb
Item number: DIM-BME100107.100
Protein function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt...
| Keywords: | Anti-DKK-1, Anti-SK, Anti-DKK1(sirexatamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H5(onvatilimab biosimilar) mAb
Item number: DIM-BME100109.100
Protein function: Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14- mediated MMP2 activation (PubMed:20666777). [The UniProt Consortium]
| Keywords: | Anti-VISTA, Anti-VSIR, Anti-Sisp-1, Anti-C10orf54, Anti-DD1alpha, Anti-Dies1, Anti-GI24, Anti-PD-1H, Anti-PP2135,... |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-TLR2(tomaralimab biosimilar) mAb
Item number: DIM-BME100110.100
Protein function: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852, PubMed:17889651). Acts via MYD88 and TRAF6,...
| Keywords: | Anti-CD282, Anti-TIL4, Anti-TLR2(tomaralimab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-LRRC15(samrotamab biosimilar) mAb
Item number: DIM-BME100111.100
| Keywords: | Anti-LIB, Anti-LRC15, Anti-LRRC15(samrotamab biosimilar) mAb |
| Host: | Chimeric Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-TSLP(tezepelumab biosimilar) mAb
Item number: DIM-BME100112.100
Protein function: [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. [The UniProt Consortium]
| Keywords: | Anti-Thymic stromal lymphopoietin, Anti-TSLP(tezepelumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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