Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human FGF2 Protein, Flag Tag
Item number: DIM-PME101612.50
Recombinant human FGF2 Protein with C-terminal 3×Flag tag. Protein function: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:8663044). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed:28302677). Binds to integrin ITGAV:ITGB3 (PubMed:28302677). Plays an important role in the...
| Keywords: | bFGF, FGFB, FGF2, FGF-2, HBGF-2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 33.7 kD |
From 139.00€
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Anti-CCR4(mogamulizumab biosimilar) mAb
Item number: DIM-BME100086.100
Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating...
| Keywords: | Anti-CC-CKR-4, Anti-CD194, Anti-ChemR13, Anti-CKR4, Anti-CMKBR4, Anti-HGCN:14099, Anti-K5-5, Anti-CCR4(mogamulizumab... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CCR2(plozalizumab biosimilar) mAb
Item number: DIM-BME100087.100
Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed:8146186, PubMed:8048929, PubMed:23408426). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium...
| Keywords: | Anti-CC-CKR-2, Anti-CCR2A, Anti-CCR2B, Anti-CD192, Anti-CKR2, Anti-CKR2A, Anti-CKR2B, Anti-CMKBR2, Anti-MCP-1-R,... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-Nectin-4(enfortumab biosimilar) mAb
Item number: DIM-BME100088.100
Protein function: Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. [The UniProt Consortium]
| Keywords: | Anti-EDSS1, Anti-LNIR, Anti-nectin-4, Anti-PRR4, Anti-PVRL4, Anti-Nectin-4(enfortumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-FCRL5(cevostamab biosimilar without anti-CD3...
Item number: DIM-BME100089.100
Protein function: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. [The UniProt Consortium]
| Keywords: | Anti-BXMAS1, Anti-CD307, Anti-CD307e, Anti-FCRH5, Anti-IRTA2, Anti-PRO820, Anti-FCRL5(cevostamab biosimilar without... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GDF15(ponsegromab biosimilar) mAb
Item number: DIM-BME100090.100
Protein function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL- expressing neurons localized in...
| Keywords: | Anti-GDF-15, Anti-MIC-1, Anti-MIC1, Anti-NAG-1, Anti-PDF, Anti-PLAB, Anti-PTGFB, Anti-GDF15(ponsegromab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GFRA3(nadecnemab biosimilar) mAb
Item number: DIM-BME100091.100
Protein function: Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. [The UniProt Consortium]
| Keywords: | Anti-GDNFR3, Anti-GFRA3(nadecnemab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-CD19(FMC63 biosimilar) mAb
Item number: DIM-BME100094.100
Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead...
| Keywords: | Anti-CD19, Anti-4, Anti-VID3, Anti-GC12802, Anti-CD19(FMC63 biosimilar) mAb |
| Host: | Mouse |
| Species reactivity: | human |
From 120.00€
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Anti-PCSK9(bococizumab biosimilar) mAb
Item number: DIM-BME100095.100
Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and...
| Keywords: | Anti-FH3, Anti-FHCL3, Anti-HCHOLA3, Anti-LDLCQ1, Anti-NARC-1, Anti-NARC1, Anti-PC9, Anti-PCSK9(bococizumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-IL1A(bermekimab biosimilar) mAb
Item number: DIM-BME100097.100
Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to...
| Keywords: | Anti-IL-1 alpha, Anti-IL-1A, Anti-IL1, Anti-IL1-ALPHA, Anti-IL1F1, Anti-IL1A(bermekimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-MIF(imalumab biosimilar) mAb
Item number: DIM-BME100098.100
Protein function: Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has...
| Keywords: | Anti-GIF, Anti-GLIF, Anti-MMIF, Anti-MIF(imalumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-NOTCH3(tarextumab biosimilar) mAb
Item number: DIM-BME100099.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of...
| Keywords: | Anti-CADASIL, Anti-CADASIL1, Anti-CASIL, Anti-IMF2, Anti-LMNS, Anti-NOTCH3(tarextumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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