Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-MAPT (etalanetug biosimilar) mAb
Item number: DIM-BME100498.100
Research use only. Protein function: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein...
| Keywords: | E-2814,E2814,E 2814, Anti-MAPTL, Anti-PHF-tau, Anti-Paired helical filament-tau, Anti-Neurofibrillary tangle protein,... |
| Species reactivity: | human |
From 120.00€
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Anti-BTLA (icatolimab biosimilar)mAb
Item number: DIM-BME100054.100
Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis...
| Keywords: | Anti-BTLA, Anti-CD272, Anti-BTLA (icatolimab biosimilar)mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Human PSMA Protein, hFc Tag
Item number: DIM-PME100390.100
Recombinant human PSMA protein with N-terminal human Fc tag. hFc(Glu99-Ala330) PSMA(Lys44-Ala750), Protein function: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of...
| Keywords: | FGCP, FOLH, GCP2, GCPII, mGCP, NAALAD1, NAALAdase, PSM, PSMA |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 105.7 kD |
From 114.00€
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Human MMP14 Protein, hFc Tag
Item number: DIM-PME100675.100
Recombinant Human MMP14 with C-terminal human Fc tag. MMP14(Tyr112-Ala541) hFc(Glu99-Ala330), Protein function: Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal...
| Keywords: | MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 75.3 kD |
From 176.00€
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Anti-OSMR(vixarelimab biosimilar) mAb
Item number: DIM-BME100148.50
Protein function: Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. [The UniProt Consortium]
| Keywords: | Anti-IL-31 receptor subunit beta, Anti-IL-31R subunit beta, Anti-IL-31R-beta, Anti-IL-31RB, Anti-OSMR(vixarelimab... |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Human CD28 Protein, mFc-His Tag
Item number: DIM-PME100014.50
Recombinant human CD28 protein with C-terminal mouse Fc and 6×His tag. CD28(Asn19-Pro152) mFc(Pro99-Lys330) 6×His, Protein function: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in...
| Keywords: | CD28, Tp44 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 68-72 kD |
From 140.00€
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Human HER3 Protein, His Tag
Item number: DIM-PME100088.50
Recombinant Human HER3 protein with C-terminal 6×His tag. HER3(Ser20-Thr643) 6×His tag, Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues...
| Keywords: | HER3, ERBB3 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 69.39 kD |
From 124.00€
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Anti-FZD10 antibody(DMC487), IgG1 Chimeric mAb
Item number: DIM-DMC100487.100
Protein function: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second...
| Keywords: | Anti-CD350, Anti-FZ-10, Anti-Fz10, Anti-FzE7, Anti-hFz10, Anti-FZD10 antibody(DMC487), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-TSHR (M22) mAb
Item number: DIM-BME100079.50
Protein function: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate...
| Keywords: | Anti-CHNG1, Anti-hTSHR-I, Anti-LGR3, Anti-TSHR (M22) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Human PSMA Protein, His Tag
Item number: DIM-PME100545.100
Recombinant human PSMA protein with N-terminal 6×His tag. 6×His tag PSMA(Lys44-Ala750), Protein function: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the...
| Keywords: | FGCP, FOLH, GCP2, GCPII, mGCP, NAALAD1, NAALAdase, PSM, PSMA |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 80.3 kD |
From 200.00€
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Human FAP (30-760) Protein, His Tag
Item number: DIM-PME100626.50
Recombinant human FAP(30-760) protein with N-terminal 6×His tag. 6×His tag FAP(Arg30-Asp760), Protein function: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation...
| Keywords: | FAP, FAPalpha, SIMP, Seprase, APCE |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 85.4 kD |
From 105.00€
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Human FCRL5(745-850)Protein, hFc Tag
Item number: DIM-PME101494.10
Recombinant human FCRL5(745-850)Protein with N-terminal human Fc tag. hFc(Glu99-Ala330)FCRL5(Val745-Thr850), Protein function: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone...
| Keywords: | CD307, FCRH5, IRTA2, BXMAS1, CD307e, PRO820 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 37.2 kD |
From 102.00€
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