Clusterin (nuclear form) (human, rec.) (His)

Human nuclear clusterin (amino acids 23-449) is fused at the C-terminus to a His-tag. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Clusterin is a secretory heterodimeric disulfide-linked glycoprotein that is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation.