Bone Morphogenetic Protein Receptor-1A, His Tag, human recombinant (rHuBMPR-1A-His)

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. (www.uniprot.org) Produced in baculovirus as a monomeric, glycosylated, polypeptide chain fused with 6xHis tag at C-terminus.