BMPR1A, Recombinant, Human, aa24-152, hIgG-His-Tag (Bone Morphogenetic Protein Receptor Type-1A, 10q

BMPR1A, also known as bone morphogenetic protein receptor type-1A, is secreted cytokines/growth factors belonging to the Transforming Growth Factor beta (TGFbeta) family. It has been shown to be overexpressed in human breast cancers. Its deletion impairs mammary tumor formation and metastasis. It plays important roles in the differentiation and development of neurons. Its expression is up-regulated during bone formation, and that they may play important roles in bone morphogenesis. Source: Recombinant protein corresponding to aa24-152 from human BMPR1A, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~41.4kD (371aa), 40-57kD (SDS-PAGE under reducing conditions), Endotoxin: <1EU/1ug (determined by LAL method), AA Sequence: ADPQNLDSML HGTGMKSDSD QKKSENGVTL APEDTLPFLK CYCSGHCPDD AINNTCITNG HCFAIIEEDD QGETTLASGC MKYEGSDFQC KDSPKAQLRR TIECCRTNLC NQYLQPTLPP VVIGPFFDGS IRLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.