Ac-ESMD-CHO (trifluoroacetate salt)

Ac-ESMD-CHO is an inhibitor of caspase-3 maturation. It inhibits proteolytic cleavage of the 32 kDa caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site, blocking formation of the p17 caspase-3 active subunit.Formal Name: N-acetyl-L-alpha-glutamyl-L-seryl-N-[(1S)-2-carboxy-1-formylethyl]-L-methioninamide, trifluoroacetate salt. Synonyms: Ac-Glu-Ser-Met-Asp-CHO. Molecular Formula: C19H30N4O10S . XCF3COOH. Formula Weight: 506.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: OC(CC[C@H](NC(C)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@H](C=O)CC(O)=O)=O)CCSC)=O)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C19H30N4O10S.C2HF3O2/c1-10(26)20-12(3-4-15(27)28)18(32)23-14(9-25)19(33)22-13(5-6-34-2)17(31)21-11(8-24)7-16(29)30,3-2(4,5)1(6)7/h8,11-14,25H,3-7,9H2,1-2H3,(H,20,26)(H,21,31)(H,22,33)(H,23,32)(H,27,28)(H,29,30),(H,6,7)/t11-,12-,13-,14-,/m0./s1. InChi Key: HZZVIJGPNMVREQ-ZMNOQRQPSA-N.