Sonstige Peptide

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3,3',5'-Triiodo-L-thyronine
3,3',5'-Triiodo-L-thyronine

Artikelnummer: Cay17598-50

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Schlagworte: 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine
Anwendung: TR Delta alpha1 activator
CAS 5817-39-0
MW: 651 D
ab 82,00 €
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Angiotensin II (human)
Angiotensin II (human)

Artikelnummer: Cay17150-25

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Schlagworte: 5-L-isoleucine-angiotensin II
Anwendung: Peptide hormone
CAS 4474-91-3
MW: 1046.2 D
ab 24,00 €
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NEU
Pam2CSK4 (trifluoroacetate salt)
Pam2CSK4 (trifluoroacetate salt)

Artikelnummer: Cay33338-1

Pam2CSK4 is a synthetic bacterial lipopeptide and an agonist of the toll-like receptor 2 (TLR2). It is selective for the TLR2/TLR6 heterodimer over TLR2/TLR1 (EC50s = 0.015 and 4.12 ng/ml, respectively, in reporter assays using human receptors). Pam2CSK4 increases the levels of inducible nitric oxide synthase (iNOS)...
Schlagworte: Pam2Cys-Ser-(Lys)4, S-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysine,...
Anwendung: Bacterial lipopeptide, TLR2 agonist
MW: 1271.8 D
ab 112,00 €
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NEU
Prosaptide TX14(A) (trifluoroacetate salt)
Prosaptide TX14(A) (trifluoroacetate salt)

Artikelnummer: Cay33935-1

Prosaptide TX14(A) is a peptide fragment of the neurotrophic factor prosaposin and an agonist of GPR37L1 and GPR37. It activates ERK signaling in HEK293T cells expressing GPR37L1 or GPR37 (EC50s = 5 and 7 nM, respectively) and inhibits forskolin-induced cAMP production in the same cells. Prosaptide TX14(A) (100 nM)...
Schlagworte: Prosaposin-derived 14-mer Peptide TX14(A),...
Anwendung: Prosaposin peptide fragment, GPR37L1 / GPR37 agonist
MW: 1579.7 D
ab 98,00 €
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Ac-QPKK(Ac)-AMC
Ac-QPKK(Ac)-AMC

Artikelnummer: Cay30790-1

Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3. It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity. AMC...
Schlagworte: Ac-Gln-Pro-Lys-Lys-(Ac)-7-amino-4-methylcoumarin, Ac-Gln-Pro-Lys-Lys-(Ac)-AMC, p53317-320 Substrate (Ac-QPKK(Ac)-AMC),...
Anwendung: Fluorogenic SIRT1 substrate
CAS 1387005-23-3
MW: 740.9 D
ab 74,00 €
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Z-Lys-OMe (hydrochloride)
Z-Lys-OMe (hydrochloride)

Artikelnummer: Cay30804-1

Z-Lys-OMe is a synthetic intermediate. It has been used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.Formal Name: N2-[(phenylmethoxy)carbonyl]-L-lysine, methyl ester, monohydrochloride. CAS Number: 26348-68-5. Molecular Formula: C15H22N2O4 . HCl. Formula Weight: 330.8. Purity: >98%....
Schlagworte: N2-[(phenylmethoxy)carbonyl]-L-lysine, methyl ester, monohydrochloride
Anwendung: Synthetic intermediate
CAS 26348-68-5
MW: 330.8 D
ab 33,00 €
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Z-Lys-OBzl (benzenesulfonate)
Z-Lys-OBzl (benzenesulfonate)

Artikelnummer: Cay30916-1

Z-Lys-OBzl is an amino acid-containing building block. It has been used in the synthesis of lysine peptide derivatives and glucosepane.Formal Name: N2-[(phenylmethoxy)carbonyl]-L-lysine, monobenzenesulfonate. CAS Number: 68973-36-4. Molecular Formula: C21H26N2O4 . C6H6O3S. Formula Weight: 528.6. Purity: >98%....
Schlagworte: N2-[(phenylmethoxy)carbonyl]-L-lysine, monobenzenesulfonate
Anwendung: Amino acid-containing building block
CAS 68973-36-4
MW: 528.6 D
ab 37,00 €
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Boc-D-Phe-Pro-OH
Boc-D-Phe-Pro-OH

Artikelnummer: Cay31151-1

Boc-D-Phe-Pro-OH is a synthetic intermediate. It has been used in the synthesis of peptide thrombin inhibitors.Formal Name: N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl-L-proline. CAS Number: 38675-10-4. Synonyms: Boc-D-FP-OH. Molecular Formula: C19H26N2O5. Formula Weight: 362.4. Purity: >98%. Formulation: A...
Schlagworte: Boc-D-FP-OH, N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl-L-proline
Anwendung: Synthetic intermediate
CAS 38675-10-4
MW: 362.4 D
ab 32,00 €
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Guanylin (human) (trifluoroacetate salt)
Guanylin (human) (trifluoroacetate salt)

Artikelnummer: Cay33140-1

Guanylin is a peptide hormone activator of membrane-bound guanylate cyclase C (GC-C). It contains four cysteines that can form disulfide bridges leading to two possible isoforms, with the active form containing disulfide bridges between Cys4 and Cys12 and Cys7 and Cys15. Guanylin is found in epithelial cells of the...
Schlagworte: L-prolylglycyl-L-threonyl-L-cysteinyl-L-alpha-glutamyl-L-isoleucyl-L-cysteinyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanyl-L-cyst...
Anwendung: GUCY2C peptide hormone activator
MW: 1458.7 D
ab 237,00 €
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RS 09 (trifluoroacetate salt)
RS 09 (trifluoroacetate salt)

Artikelnummer: Cay33152-1

RS 09 is a peptide agonist of toll-like receptor 4 (TLR4). It activates NF-kappaB in a concentration-dependent manner in a secreted alkaline phosphatase (SEAP) assay using TLR4-expressing HEK293 cells and induces NF-kappaB nuclear translocation in the same cells. It also induces cytokine secretion from RAW 264.7...
Schlagworte: Ala-Pro-Pro-His-Ala-Leu-Ser, APPHALS, L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine, trifluoroacetate salt
Anwendung: TLR4 agonist
MW: 691.8 D
ab 80,00 €
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alpha-NAAG
alpha-NAAG

Artikelnummer: Cay33337-10

alpha-NAAG is a peptide neurotransmitter that is widely expressed throughout mammalian central and peripheral nervous systems. Following synaptic release, alpha-NAAG activates postsynaptic metabotropic glutamate receptor 3 (mGluR3) to inhibit cAMP production in neurons and astrocytes, as well as acts on presynaptic...
Schlagworte: NAAG, N-Acetylaspartylglutamic Acid, alpha-Spaglumic Acid, N-acetyl-alpha-L-aspartyl-L-glutamic acid
Anwendung: Peptide neurotransmitter, MGluR3 agonist
CAS 3106-85-2
MW: 304.3 D
ab 62,00 €
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COG133 (trifluoroacetate salt)
COG133 (trifluoroacetate salt)

Artikelnummer: Cay33587-1

COG133 is a peptide fragment of ApoE that corresponds to residues 133-149 of the ApoE LDL receptor-binding domain and an antagonist of alpha7 nicotinic acetylcholine receptors (nAChRs, IC50 = 720 nM). It suppresses TNF-alpha and nitric oxide (NO) release in BV-2 microglia when used at concentrations ranging from 10...
Schlagworte: Ac-LRVRLASHLRKLRKRLL-NH2, ApoE (133-149),...
Anwendung: ApoE peptide fragment, Alpha7 nAChR antagonist
CAS 514200-66-9
MW: 2169.7 D
ab 109,00 €
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