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3,3',5'-Triiodo-L-thyronine
Artikelnummer: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
| Schlagworte: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
| Anwendung: | TR Delta alpha1 activator |
| CAS | 5817-39-0 |
| MW: | 651 D |
ab 114,00 €
Angiotensin II (human) (acetate)
Artikelnummer: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
| Schlagworte: | 5-L-isoleucine-angiotensin II, acetate |
| Anwendung: | Peptide hormone |
| CAS | 68521-88-0 |
| MW: | 1046.2 D |
ab 34,00 €
Tentoxin
Artikelnummer: Cay11442-1
Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...
| Schlagworte: | cyclo[N-methyl-L-alanyl-L-leucyl-(alphaZ)-alpha,beta-didehydro-N-methylphenylalanylglycyl] |
| Anwendung: | Herbicide, chloroplast development inhibitor |
| CAS | 28540-82-1 |
| MW: | 414.5 D |
ab 259,00 €
Glucagon (hydrochloride)
Artikelnummer: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
| Schlagworte: | glucagon (swine) |
| Ursprungsart: | swine |
| CAS | 19179-82-9 |
| MW: | 3482.8 D |
ab 117,00 €
Survodutide
Artikelnummer: Cay40972-1
Survodutide is a dual peptide agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR). It increases cAMP accumulation in CHO-K1 cells expressing GLP-1R or GCGR in reporter assays (EC50s = 0.33 and 0.52 nM, respectively) and potentiates glucose-induced insulin secretion in isolated...
| Schlagworte: | BI-456906,... |
| Anwendung: | GLP-1R / GCGR dual peptide agonist |
| CAS | 2805997-46-8 |
| MW: | 4231.7 D |
ab 88,00 €
GLP-1 (28-36) amide (trifluoroacetate salt)
Artikelnummer: Cay41249-1
Glucagon-like peptide 1 (GLP-1) (28-36) amide is a peptide and an active metabolite of the endogenous GLP-1R agonist GLP-1 (7-36) amide (Cay-15069). It is formed from GLP-1 (7-36) amide by neprilysin (NEP). GLP-1 (28-36) amide (100 nM) inhibits decreases in ATP levels induced by hydrogen peroxide and increases in...
| Schlagworte: | Glucagon-like Peptide 1 (28-36) amide, Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2,... |
| Anwendung: | Peptide, active GLP-1 (7-36) amide metabolite |
| MW: | 1088.4 D |
ab 38,00 €
Dapiglutide (sodium salt)
Artikelnummer: Cay41259-1
Dapiglutide is a dual glucagon-like peptide 1 receptor (GLP-1R) and GLP-2R agonist. It induces cAMP accumulation in HEK293 cells expressing human GLP-1R or GLP-2R (EC50s = 190 and 210 pM, respectively). Dapiglutide (6 nmol/kg) reduces peak blood glucose levels in an oral glucose tolerance test and increases...
| Schlagworte: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-seryl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-ala... |
| Anwendung: | Dual GLP-1R / GLP-2R agonist |
| MW: | 4166.8 D |
ab 254,00 €
Glepaglutide (acetate)
Artikelnummer: Cay41274-1
Glepaglutide is a peptide agonist of the glucagon-like peptide 2 receptor (GLP-2R). It selectively induces cAMP accumulation in HEK293 cells expressing GLP-2R over those expressing GLP-1R (EC50s = 0.24 and 8.7 nM, respectively, for the human receptors). Glepaglutide (10 mg/kg per day for 26 weeks) increases mucosal...
| Schlagworte: | ZP1848 |
| Anwendung: | Peptide, GLP-2R agonist |
| MW: | 4316.1 D |
ab 119,00 €
Utreglutide
Artikelnummer: Cay41275-1
Utreglutide is a G protein-biased peptide agonist of glucagon-like peptide 1 receptor (GLP-1R). It selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R over beta-arrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s = 0.63 and 79 nM, respectively). Utreglutide induces insulin...
| Schlagworte: | GL0034,... |
| Anwendung: | G-protein-biased peptide GLP-1R agonist |
| CAS | 2460862-12-6 |
| MW: | 4166.7 D |
ab 97,00 €
HOXB7 (8-25) (human)
Artikelnummer: Cay41334-1
HOXB7 (8-25) is a peptide fragment of the transcription factor homeobox protein B7 (HOXB7).Formal Name:...
| Schlagworte: | Homeobox Protein B7 (8-25),... |
| Anwendung: | HOXB7 peptide fragment |
| MW: | 1848 D |
ab 39,00 €
![Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH](https://www.biomol.com/media/image/20/78/09/Cay40707-1_200x200.png "Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH")
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH
Artikelnummer: Cay40707-1
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide (Cay-40231, Cay-29969, Cay-40170).Formal Name:...
| Schlagworte: | Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH,... |
| Anwendung: | Semaglutide synthesis building block |
| CAS | 1662688-20-1 |
| MW: | 1196.5 D |
ab 234,00 €
Cotadutide (acetate)
Artikelnummer: Cay40714-1
Cotadutide is a synthetic peptide and dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR) that is biased toward GLP-1R. It increases cAMP accumulation in CHO cells overexpressing recombinant human GLP-1R or GCGR (EC50s = 6.9 and 10.2 pM, respectively). It also enhances...
| Schlagworte: | MEDI0382 |
| Anwendung: | GLP-1R / GCGR dual agonist, synthetic peptide |
| MW: | 3788.1 D |
ab 133,00 €