Sonstige Peptide

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MOTS-c (human)
MOTS-c (human)

Artikelnummer: AG-CP3-0026-M001

Solid lyophilized powder. Soluble in water. Mitochondria-derived peptide (MDP), Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK), Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in...
Schlagworte: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA, Mitochondrial Open Reading Frame of the 12S...
Anwendung: Mitochondria-derived peptide, AMPK promoter
CAS 1627580-64-6
MW: 2288,6 D
ab 165,00 €
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AAF-CMK (trifluoroacetate salt)
AAF-CMK (trifluoroacetate salt)

Artikelnummer: Cay14461-5

Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 µM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome....
Schlagworte: N-Ala-Ala-Phe-CMK, Tripeptidyl Peptidase Inhibitor II,...
Anwendung: TPPII inhibitor, Bleomycin hydrolase and aminopeptidase inhibitor
CAS 184901-82-4
MW: 453.8 D
ab 62,00 €
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Iberiotoxin
Iberiotoxin

Artikelnummer: Cay14608-100

Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium ion-activated potassium ion channels (BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by BKCa in excised membrane patches from bovine aortic...
Schlagworte: 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic...
Anwendung: BKCa blocker
CAS 129203-60-7
MW: 4230.9 D
249,00 €
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Apamin
Apamin

Artikelnummer: Cay17082-500

Apamin is an 18 amino acid peptide toxin found in bee venom. It is a potent blocker of small conductance Ca2+-activated K+ (SK, KCa2) channels that is more effective at SK2 than SK1 and SK3 (IC50 values are 0.06-0.4, 1-12, and 1-13 nM, respectively). It is ineffective against SK4 at 1 µM. Apamin is used to elucidate...
Schlagworte: Ro 23-6721, CNCKAPETALCARRCQQH (Modifications: Disulfide bridge between 1 - 11, 3 - 15, His-18 = C-terminal amide)
Anwendung: Bee venom toxin, KCa2 blocker
CAS 24345-16-2
MW: 2027.3 D
157,00 €
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A-54556B
A-54556B

Artikelnummer: Cay17090-500

A-54556B is a natural acyldepsipeptide (ADEP) antibiotic isolated from the fermentation broth of S. hawaiiensis. Like the closely related ADEP, A-54556A (Cay-15305), A-54556B is effective against Gram-positive bacteria, including penicillin-resistant S. aureus. A-54556B is also effective against many strains of...
Schlagworte: A-54556 Factor B, (6->2)-lactone...
Anwendung: Gram-positive bacterial antibiotic
CAS 1629166-56-8
MW: 704.8 D
ab 325,00 €
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Enopeptin A
Enopeptin A

Artikelnummer: Cay17092-500

Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus...
Schlagworte: BRN 537924, NSC 657143,...
Anwendung: Gram-positive bacterial antibiotic
CAS 139601-96-0
MW: 896 D
ab 374,00 €
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Micrococcin P1
Micrococcin P1

Artikelnummer: Cay17093-500

Micrococcin P1 is a macrocyclic peptide antibiotic that functions as an acceptor-site-specific inhibitor of ribosomal protein synthesis, effectively preventing the growth of Gram-positive bacteria without affecting that of Gram-negative bacteria.
Schlagworte: 2'-[(11S,14Z,21S,28S)-14-ethylidene-9,10,11,12,13,14,20,21,27,28-decahydro-28-[(1R)-1-hydroxyethyl]-11-[(1R)-1-hydroxyethy...
Anwendung: Gram-positive bacterial antibiotic
CAS 67401-56-3
MW: 1144.4 D
ab 394,00 €
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Pyridomycin
Pyridomycin

Artikelnummer: Cay17095-500

Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis,...
Schlagworte: Erizomycin, NSC 246134,...
Anwendung: Antimycobacterial enoyl ACP reductase inhA inhibitor
CAS 18791-21-4
MW: 540.6 D
ab 374,00 €
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alpha-Amanitin
alpha-Amanitin

Artikelnummer: Cay17898-1

alpha-Amanitin is a cyclic peptide found in several species of the Amanita genus as well as other poisonous fungi. At 1, 10, and 50 µg/ml, respectively, alpha-amanitin inhibits RNA polymerase II, III, and IV, preventing translocation of the enzymes on DNA, which significantly slows the rate of transcription. RNA...
Schlagworte: alpha-Amanitin
Anwendung: RNA polymerase inhibitor
CAS 23109-05-9
MW: 919 D
219,00 €
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Phalloidin
Phalloidin

Artikelnummer: Cay18039-1

Phalloidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds F-actin and stabilizes actin fibers. Fluorescently labeled phalloidin is commonly used to stain F-actin in cells.
Schlagworte: NSC 523214, phalloidin
Anwendung: Actin fiber stabilizer
CAS 17466-45-4
MW: 788.9 D
199,00 €
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beta-Amanitin
beta-Amanitin

Artikelnummer: Cay18142-1

beta-Amanitin is a cyclic peptide found in several species of the Amanita genus, as well as other poisonous fungi. It inhibits RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase, thus preventing mammalian protein synthesis. The biological activity of this toxin is similar to that of...
Schlagworte: 1-L-aspartic acid-alpha-amanitin
Anwendung: RNA polymerase inhibitor
CAS 21150-22-1
MW: 920 D
224,00 €
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Phallacidin
Phallacidin

Artikelnummer: Cay18146-1

Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds filamentous actin (F-actin) like phalloidin (Cay-18039), but contains a carboxyl group for coupling reactions.
Schlagworte: cyclic...
Anwendung: Actin fiber binding, Carboxyl group for coupling reactions
CAS 26645-35-2
MW: 846.9 D
219,00 €
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