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Ac-DEVD-AFC
Artikelnummer: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
| Anwendung: | Caspase-3 substrate |
| CAS | 201608-14-2 |
145,00 €
Ac-DEVD-AMC
Artikelnummer: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
| Anwendung: | Caspase-3 substrate |
| CAS | 169332-61-0 |
145,00 €
(Z-DEVD)2-R110
Artikelnummer: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
| Anwendung: | Caspase-3 substrate, Caspase-7 substrate |
145,00 €
(Ac-PAL)2R110
Artikelnummer: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
145,00 €
PI-3 Kinase Lipid Substrate
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
| Anwendung: | PI-3 kinase substrate |
581,00 €
NEU
Cdk2 Peptide Substrate (trifluoroacetate salt)
Artikelnummer: Cay44656-10
Cdk2 peptide substrate is an optimal peptide substrate of Cdk2. It binds across the Cdk2 catalytic site when in complex with Cdk2 phosphorylated at T160 and cyclin A3. Cdk2 peptide substrate has been used in enzyme assays for Cdk2 activity.. SMILES:...
| Schlagworte: | Cyclin-dependent Kinase 2 Peptide Substrate, His-His-Ala-Ser-Pro-Arg-Lys-OH,... |
| Anwendung: | Optimal Cdk2 peptide substrate |
| MW: | 831.94 D |
ab 45,00 €
(BOC-VPR)2R110
Artikelnummer: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Anwendung: | Fluorogenic alpha-thrombin substrate |
145,00 €
MeOSuc-AAPV-pNA
Artikelnummer: Cay17601-10
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to...
| Schlagworte: | N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide |
| Anwendung: | Neutrophil elastase & PR3 substrate |
| CAS | 70967-90-7 |
| MW: | 590.6 D |
ab 101,00 €
(Ac-WLA)2R110
Artikelnummer: ABD-13468
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
145,00 €
Bortezomib
Artikelnummer: Cay10008822-1
Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...
| Schlagworte: | LDP-341, MG-341, MLN341, NSC 681239, PS-341,... |
| Anwendung: | Proteasome subunit beta type-1/5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384.2 D |
ab 55,00 €
Pepstatin
Artikelnummer: LKT-P1761.25
An inhibitor of acid proteases isolated from streptomyces. It has been shown to induce contractile effects on rat aorta rings.
| Schlagworte: | Pepstatin A |
| Anwendung: | Aspartyl Protease inhibitor |
| CAS | 26305-03-3 |
| MW: | 685,89 D |
ab 127,00 €
Ac-IETD-AFC
Artikelnummer: ABD-13410
A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.
| Anwendung: | Caspase-8 substrate |
| CAS | 211990-57-7 |
291,00 €