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Ac-DEVD-AFC Artikelnummer: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
| Anwendung: | Caspase-3 substrate |
| CAS | 201608-14-2 |
112,00 €
Ac-DEVD-AMC Artikelnummer: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
| Anwendung: | Caspase-3 substrate |
| CAS | 169332-61-0 |
112,00 €
(Z-DEVD)2-R110 Artikelnummer: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
| Anwendung: | Caspase-3 substrate, Caspase-7 substrate |
112,00 €
(Ac-PAL)2R110 Artikelnummer: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
112,00 €
MCL-1 Peptide Ligand Artikelnummer: BPS-79507
MCL-1 Peptide Ligand is useful as a substrate for screening services and optimized for use with the following TR-FRET assay kits: * MCL-1 TR-FRET Assay kit (BPS-79506) * MCL-1 TR-FRET Assay kit (Mouse) (BPS-79928)
| Anwendung: | Substrate, Screening, TR-FRET |
| MW: | 3162 D |
247,00 €
Ac-QPKK(Ac)-AMC Artikelnummer: Cay30790-1
Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3. It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity. AMC...
| Schlagworte: | Ac-Gln-Pro-Lys-Lys-(Ac)-7-amino-4-methylcoumarin, Ac-Gln-Pro-Lys-Lys-(Ac)-AMC, p53317-320 Substrate (Ac-QPKK(Ac)-AMC),... |
| Anwendung: | Fluorogenic SIRT1 substrate |
| CAS | 1387005-23-3 |
| MW: | 740.9 D |
ab 74,00 €
Z-(L-Arg)-AMC (hydrochloride) Artikelnummer: Cay30797-10
Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H. Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission...
| Schlagworte: | Bz-Arg-AMC, N-benzoxy-L-Arg-7-amido-4-methylcoumarin, N-benzoyl-L-Arg-AMC, Z-Arg(HCl)AMC,... |
| Anwendung: | Fluorogenic trypsin substrate |
| CAS | 70375-22-3 |
| MW: | 502 D |
ab 69,00 €
RR-Src (trifluoroacetate salt) Artikelnummer: Cay33579-1
RR-Src is a synthetic peptide substrate that corresponds to the sequence in Src surrounding the tyrosine subject to phosphorylation. It is a substrate for EGF-mediated tyrosine phosphorylation. RR-Src inhibits IL-2-induced proliferation of cytotoxic T cells.Formal Name:...
| Schlagworte: | Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly, RRLIEDAEYAARG, Src-Peptide,... |
| Anwendung: | Synthetic peptide substrate |
| MW: | 1519.7 D |
ab 62,00 €
(BOC-VPR)2R110 Artikelnummer: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Anwendung: | Fluorogenic alpha-thrombin substrate |
112,00 €
(Ac-WLA)2R110 Artikelnummer: ABD-13468
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
112,00 €
Ac-IETD-AFC Artikelnummer: ABD-13410
A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.
| Anwendung: | Caspase-8 substrate |
| CAS | 211990-57-7 |
230,00 €
Bortezomib Artikelnummer: Cay10008822-1
Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...
| Schlagworte: | LDP-341, MG-341, MLN341, NSC 681239, PS-341,... |
| Anwendung: | Proteasome subunit beta type-1/5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384.2 D |
ab 32,00 €