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Substrate und Inhibitoren

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Z-LRGG-AMC (trifluoroacetate salt)
Z-LRGG-AMC (trifluoroacetate salt)

Artikelnummer: Cay26641-50

Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Schlagworte: Z-Leu-Arg-Gly-Gly-7-amino-4-methylcoumarin, Z-Leu-Arg-Gly-Gly-AMC,...
Anwendung: Fluorogenic isopeptidase T substrate
CAS 167698-68-2
MW: 692.8 D
ab 107,00 €
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N-(p-Tosyl)-GPR-pNA (acetate)
N-(p-Tosyl)-GPR-pNA (acetate)

Artikelnummer: Cay27568-50

N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin. Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.
Schlagworte: N-(p-Tosyl)-Gly-Pro-Arg-p-Nitroanilide, Tos-Gly-Pro-Arg-pNA,...
Anwendung: Photometric thrombin substrate
CAS 86890-95-1
MW: 662.7 D
ab 157,00 €
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Z-D-Arg-Gly-Arg-pNA (hydrochloride)
Z-D-Arg-Gly-Arg-pNA (hydrochloride)

Artikelnummer: Cay27583-5

Z-D-Arg-Gly-Arg-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Arg-Gly-Arg (RGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.
Schlagworte: Benzyl-D-Arg-Gly-Arg-pNA, Benzyl-D-Arg-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate, S-2765,...
Anwendung: Photometric Factor Xa substrate
CAS 113711-77-6
MW: 714.6 D
ab 49,00 €
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NEU
D-Pro-Phe-Arg-pNA (hydrochloride)
D-Pro-Phe-Arg-pNA (hydrochloride)

Artikelnummer: Cay27569-50

D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.
Schlagworte: D-Pro-Phe-Arg-p-nitroaniline, pFR-pNA, Plasma Kallikrein Chromogenic Substrate,...
Anwendung: Photometric plasma kallikrein substrate
CAS 62354-56-7
MW: 611.5 D
ab 82,00 €
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NEU
MeO-Suc-RPY-pNA (hydrochloride)
MeO-Suc-RPY-pNA (hydrochloride)

Artikelnummer: Cay27706-5

MeO-Suc-RPY-pNA is a colorimetric substrate for serine proteases, including trypsin, chymotrypsin, kallikrein-related peptidase 7 (KLK7), and kallikrein-related peptidase 3/prostate-specific antigen. Serine proteases preferentially bind to and cleave the Arg-Pro-Tyr (RPY) peptide sequence to release p-nitroanilide...
Schlagworte: Methoxy-Succinyl-Arg-Pro-Tyr-pNA, Methoxy-Succinyl-Arg-Pro-Tyr-p-nitroanilide, S 2586, Serine Protease Chromogenic...
Anwendung: Photometric serine protease substrate
MW: 668.7 D
ab 32,00 €
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NEU
Bz-Nle-KRR-AMC (hydrochloride)
Bz-Nle-KRR-AMC (hydrochloride)

Artikelnummer: Cay27710-5

Bz-Nle-KRR-AMC is a fluorogenic peptide substrate for yellow fever virus (YFV) non-structural 3 (NS3) and dengue virus (DV) NS2B/3 serine proteases. Upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify YFV NS3 or DV...
Schlagworte: Benzoyl-Nle-Lys-Arg-Arg-7-amino-4-methylcoumarin, Benzoyl-Nle-Lys-Arg-Arg-AMC, Bz-Nle-Lys-Arg-Arg-AMC,...
Anwendung: Fluorogenic YFV NS3 peptide substrate
CAS 863975-32-0
MW: 83.3 D
ab 32,00 €
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NEU
Ac-QQQ-AMC (hydrochloride)
Ac-QQQ-AMC (hydrochloride)

Artikelnummer: Cay27711-5

Ac-QQQ-AMC is a fluorogenic probe. L-Glutamine tripeptide (QQQ) is a substrate for peptidoglutaminase I and II from the bacterium B. circulans. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Schlagworte: Ac-Gln-Gln-Gln-7-amino-4-methylcoumarin, Ac-Gln-Gln-Gln-AMC, Ac-L-Gln-L-Gln-L-Gln-AMC,...
Anwendung: Fluorogenic probe, B. circulans peptidoglutaminase I & II substrate
MW: 601.6 D
ab 32,00 €
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Bz-IEGR-pNA (acetate)
Bz-IEGR-pNA (acetate)

Artikelnummer: Cay27567-5

Bz-IEGR-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.
Schlagworte: Bz-Ile-Glu-Gly-Arg-pNA, Bz-Ile-Glu-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate,...
Anwendung: Photometric Factor Xa substrate
CAS 1325307-57-0
MW: 7578 D
ab 32,00 €
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Histone H3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
Histone H3 (23-34) (human, mouse, rat, bovine)...

Artikelnummer: Cay28139-1

Histone H3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. It contains lysine residues at positions 23 and 27 that are subject to methylation and acetylation and have a role in the regulation of gene expression and a serine...
Schlagworte: KAARKSAPATGG, L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycine,...
Anwendung: Peptide fragment, Methylation / acetylation / phosphorylation studies
MW: 1114.3 D
249,00 €
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Histone H3 (69-89) amide (human, mouse, rat, bovine) (trifluoroacetate salt)
Histone H3 (69-89) amide (human, mouse, rat, bovine)...

Artikelnummer: Cay28146-1

Histone H3 (69-89) amide is a peptide fragment of histone H3 that corresponds to amino acid residues 70-90 of the human histone H3.1 and H3.2 sequences. Histone H3 (69-89) amide contains a lysine residue at position 79 that is subject to methylation and acetylation and has a role in regulation of gene expression.
Schlagworte: RLVREIAQDFKTDLRFQSSAV-NH2,...
Anwendung: Peptide fragment, Methylation / acetylation studies
MW: 2478.8 D
312,00 €
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alpha-Bungarotoxin
alpha-Bungarotoxin

Artikelnummer: Cay16385-1

alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
Schlagworte: alpha-Bgt, alpha-BTX, alpha-bungarotoxin
Anwendung: Irreversible nicotinic acetylcholine receptor blocker
CAS 11032-79-4
MW: 7984.2 D
187,00 €
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Pepstatin
Pepstatin

Artikelnummer: LKT-P1761.25

An inhibitor of acid proteases isolated from streptomyces. It has been shown to induce contractile effects on rat aorta rings.
Schlagworte: Pepstatin A
Anwendung: Aspartyl Protease inhibitor
CAS 26305-03-3
MW: 685,89 D
ab 87,00 €
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