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Ac-DEVD-AFC
Artikelnummer: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
| Anwendung: | Caspase-3 substrate |
| CAS | 201608-14-2 |
139,00 €
(Z-DEVD)2-R110
Artikelnummer: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
| Anwendung: | Caspase-3 substrate, Caspase-7 substrate |
139,00 €
Ac-DEVD-AMC
Artikelnummer: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
| Anwendung: | Caspase-3 substrate |
| CAS | 169332-61-0 |
139,00 €
(Ac-PAL)2R110
Artikelnummer: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
139,00 €
PI-3 Kinase Lipid Substrate
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
| Anwendung: | PI-3 kinase substrate |
569,00 €
NEU
LL-37 (13-37) (human) (trifluoroacetate salt)
Artikelnummer: Cay36949-1
LL-37 (13-37) is an anticancer peptide fragment of LL-37 (Cay-24461). It inhibits the ATPase activity of ATP-binding cassette transporter 2, subfamily G (ABCG2) when used at a concentration of 1 µM. LL-37 (13-37) induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-glycoprotein (P-gp), also...
| Schlagworte: | CAP-18, Cathelicidin, FALL-39, hCAP-18, IG-25, LL-13, LL-25,... |
| Anwendung: | LL-37 anticancer peptide fragment |
| MW: | 3043.6 D |
ab 53,00 €
NEU
CXCL9 (74-103) (human) (trifluoroacetate salt)
Artikelnummer: Cay38849-1
Chemokine (C-X-C motif) ligand 9 (CXCL9) (74-103) is a C-terminal fragment of mature CXCL9. It binds to the glycosaminoglycan heparin in a cell-free assay (Kd = 3.1 nM). CXCL9 (74-103) inhibits the binding of CXCL8 or CXCL11 to heparin, as well as chemokine (C-C motif) ligand 2 (CCL2) binding to heparan sulfate, in...
| Schlagworte: | Chemokine (C-X-C motif) Ligand 9 (74-103), MIG30, Monokine Induced by Interferon-gamma (74-103) |
| Anwendung: | CXCL9-derived peptide |
| MW: | 3661.4 D |
ab 66,00 €
NEU
Aureobasidin A
Artikelnummer: Cay39722-10
Aureobasidin A is a cyclic depsipeptide that has been found in A. pullulans and has diverse biological activities. It inhibits inositol phosphorylceramide synthase, an enzyme involved in sphingolipid biosynthesis (Kis = 0.18 and 0.23 for the C. albicans and S. cerevisiae enzymes, respectively). Aureobasidin A also...
| Schlagworte: | Antibiotic R 106I, Basifungin, LY295337, NK 204, R 106-1,... |
| Anwendung: | Bioactive cyclic depsipeptide |
| CAS | 127785-64-2 |
| MW: | 1101.4 D |
ab 218,00 €
NEU
Retatrutide (sodium salt)
Artikelnummer: Cay39747-1
Retatrutide is a triple agonist of the glucagon receptor (GCGR), glucagon-like peptide 1 receptor (GLP-1R), and gastric inhibitory polypeptide receptor (GIP receptor), also known as the glucose-dependent insulinotropic polypeptide receptor. It induces cAMP accumulation in HEK293 cells expressing the human GCGR,...
| Schlagworte: | LY3437943,... |
| Anwendung: | GCGR / GLP-1R / GIPR triple agonist |
| MW: | 4731.3 D |
ab 77,00 €
NEU
PE 22-28 (acetate)
Artikelnummer: Cay39986-1
PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin (Cay-36762). It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the...
| Schlagworte: | Gly-Val-Ser-Trp-Gly-Leu-Arg-OH, glycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, acetate |
| Anwendung: | K2P2.1/TREK1 peptide inhibitor |
| MW: | 773.9 D |
ab 119,00 €
![[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)](https://www.biomol.com/media/image/a1/b0/cc/Cay40149-1_200x200.png "[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)")
[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)
Artikelnummer: Cay40149-1
[pGlu4]-Myelin basic protein peptide is a substrate for PKC. It is selectively phosphorylated by PKC over PKA and phosphorylase kinase.Formal Name: 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt. Synonyms: [pGlu4]-MBP Peptide....
| Schlagworte: | [pGlu4]-MBP Peptide,... |
| Anwendung: | PKC peptide substrate |
| MW: | 1373.6 D |
ab 34,00 €
Malantide (trifluoroacetate salt)
Artikelnummer: Cay40150-1
Malantide is a synthetic peptide derived from the beta-subunit of human phosphorylase kinase and is a fluorescent substrate for PKA and PKC. Upon phosphorylation by PKA or PKC, the intrinsic tyrosine fluorescence decreases and can be used to quantify PKA and PKC activity. Malantide displays an emission at 302 nm...
| Schlagworte: | L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-serylglycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-... |
| Anwendung: | Fluorescent PKA / PKC substrate |
| MW: | 1633.9 D |
ab 61,00 €