Buccalin A (trifluoroacetate salt)

Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling. It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10 nM. Buccalin A (10 µM) decreases the amplitude of inhibitory post-synaptic currents (IPSCs) in isolated and perfused voltage-clamped A. californica buccal ganglia.Formal Name: (3S,6S,9S,12S,15S,18S,27S)-3-((S)-2-(2-aminoacetamido)-4-(methylthio)butanamido)-15-benzyl-27-carbamoyl-6,18-bis(hydroxymethyl)-9-isobutyl-12,29-dimethyl-4,7,10,13,16,19,22,25-octaoxo-5,8,11,14,17,20,23,26-octaazatriacontanoic acid, trifluoroacetate salt. Molecular Formula: C45H72N12O15S . XCF3COOH. Formula Weight: 1053.2. Purity: >98%. Formulation: (Request formulation change), A solid. Peptide Sequence: GMDSLAFSGGL-NH2. Solubility: Water: Soluble. SMILES: [H]NCC(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(NCC(NCC(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)CC1=CC=CC=C1)=O)C)=O)=O)=O)CC(O)=O)=O)CCSC)=O.FC(F)(F)C(O)=O. InChi Code: InChI=1S/C45H72N12O15S.C2HF3O2/c1-23(2)14-28(38(47)65)52-36(62)20-48-35(61)19-49-40(67)32(21-58)56-43(70)30(16-26-10-8-7-9-11-26)53-39(66)25(5)50-42(69)29(15-24(3)4)54-45(72)33(22-59)57-44(71)31(17-37(63)64)55-41(68)27(12-13-73-6)51-34(60)18-46,3-2(4,5)1(6)7/h7-11,23-25,27-33,58-59H,12-22,46H2,1-6H3,(H2,47,65)(H,48,61)(H,49,67)(H,50,69)(H,51,60)(H,52,62)(H,53,66)(H,54,72)(H,55,68)(H,56,70)(H,57,71)(H,63,64),(H,6,7)/t25-,27-,28-,29-,30-,31-,32-,33-,/m0./s1. InChi Key: KNOFCWVPSRPVHF-KXYLNWTBSA-N.