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3,3',5'-Triiodo-L-thyronine
Artikelnummer: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
| Schlagworte: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
| Anwendung: | TR Delta alpha1 activator |
| CAS | 5817-39-0 |
| MW: | 651 D |
ab 114,00 €
Angiotensin II (human) (acetate)
Artikelnummer: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
| Schlagworte: | 5-L-isoleucine-angiotensin II, acetate |
| Anwendung: | Peptide hormone |
| CAS | 68521-88-0 |
| MW: | 1046.2 D |
ab 34,00 €
Glucagon (hydrochloride)
Artikelnummer: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
| Schlagworte: | glucagon (swine) |
| Ursprungsart: | swine |
| CAS | 19179-82-9 |
| MW: | 3482.8 D |
ab 117,00 €
NEU
Strep-tag(R)II peptide
Artikelnummer: IBA-2-1018-002
Synthetic Strep-tag(R)II peptide recognized by Strep-Tactin(R), Strep-Tactin(R)XT as well as the monoclonal antibodies, StrepMAB-Classic and StrepMAB-Immo. It can be used for competitive elution of Strep-tag(R)II fusion proteins or as control protein in dot blot assays.
| Anwendung: | Synthetic peptide recognized by Strep-Tactin(R) / Strep-Tactin(R)XT |
100,00 €
NEU
Sulfo-SMCC (sodium salt)
Artikelnummer: Cay35692-100
Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to...
| Schlagworte: | Sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate,... |
| Anwendung: | Water-soluble protein cross-linking reagent |
| CAS | 92921-24-9 |
| MW: | 436.4 D |
ab 92,00 €
NEU
![[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)](https://www.biomol.com/media/image/ca/29/2a/Cay39017-1_200x200.png "[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)")
[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)
Artikelnummer: Cay39017-1
[Ala1,3,11,15]-Endothelin-1 is an endothelin receptor type B (ETB) agonist and linear synthetic peptide derivative of endothelin-1 in which all four cysteine residues have been substituted with alanine. It selectively binds to ETB over ETA receptors (IC50s = 0.33 and 570 nM, respectively, for the porcine receptors)....
| Schlagworte: | [Ala1,3,11,15]-ET-1, 4-Ala-ET-1,... |
| Anwendung: | ETB receptor agonist |
| MW: | 2367.7 D |
ab 53,00 €
NEU
![[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate salt)](https://www.biomol.com/media/image/b8/fa/ce/Cay40152-1_200x200.png "[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate salt)")
[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate...
Artikelnummer: Cay40152-1
[Asp371]-Tyrosinase (369-377) is a naturally occurring tyrosinase antigen peptide. It is formed via post-translational modification of Asn371. [Asp371]-Tyrosinase (369-377) binds to MHC class I subtype HLA-A*0201-positive T2 cells (IC50 = 1.2 µg/ml) and induces lysis of HLA-A2.1-positive T2 cells incubated with...
| Schlagworte: | [Asp370]-Tyrosinase (368-376), Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val,... |
| Anwendung: | Tyrosinase antigen peptide |
| MW: | 1031.2 D |
ab 34,00 €
NEU
MDM2 (32-46) (trifluoroacetate salt)
Artikelnummer: Cay38836-1
MDM2 (32-46) is a peptide fragment of MDM2. Formal Name: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-L-glutaminyl-L-lysyl-L-aspartic acid, trifluoroacetate salt. Molecular Formula: C75H135N19O20 XCF3COOH. Formula Weight: 1623.0. Purity:...
| Schlagworte: | ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-... |
| MW: | 1623 D |
ab 36,00 €
NEU
![[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate)](https://www.biomol.com/media/image/21/91/63/Cay40298-1_200x200.png "[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate)")
[Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig,...
Artikelnummer: Cay40298-1
[Gly8,36,Glu22]-Glucagon-like peptide 1 ([Gly8,36,Glu22]-GLP-1) (7-37) is a derivative of GLP-1 containing alanine-to-glycine, glycine-to-glutamate, and arginine-to-glycine substitutions at positions 8, 22, and 36, respectively, and a peptide fragment of the GLP-1 receptor (GLP-1R) agonist dulaglutide.Formal Name:...
| Schlagworte: | [Gly8,36,Glu22]-Glucagon-like Peptide 1 (7-37),... |
| Anwendung: | Dulaglutide fragment, GLP-1 derivative |
| MW: | 3314.6 D |
ab 47,00 €
NEU
Mechercharmycin A
Artikelnummer: Cay40868-1
Mechercharmycin A is a cyclic peptide originally isolated from Thermoactinomyces that has anticancer activity. It induces cytotoxicity in A549 lung cancer and Jurkat leukemia cells (IC50s = 40 and 46 nM, respectively).Formal Name:...
| Schlagworte: | IB-01211,... |
| Anwendung: | Cyclic peptide, anticancer agent |
| CAS | 822520-96-7 |
| MW: | 708.7 D |
784,00 €
Exendin-4 (3-39) amide (trifluoroacetate salt)
Artikelnummer: Cay36912-1
Exendin-4 (3-39) amide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and an active metabolite of exendin-4 (48-86) amide (Cay-11096). It is formed from exendin-4 (48-86) amide in rat liver homogenates. Exendin-4 (3-39) amide induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = 9...
| Schlagworte: | Exendin (3-39),... |
| Anwendung: | GLP-1R agonist, active exendin-4 (48-86) amide metabolite |
| MW: | 3992.4 D |
ab 47,00 €
Fz7-21 (trifluoroacetate salt)
Artikelnummer: Cay36922-1
Fz7-21 is a peptide antagonist of the frizzled family G protein-coupled receptor 7 (FZD7, IC50 = 100 nM). It inhibits Wnt3a-induced beta-catenin signaling in a reporter assay using HEK293 cells. Fz7-21 (100 µM) reduces the number of cells positive for leucine-rich alpha-2-glycoprotein 5 (Lrg5), a marker of...
| Schlagworte: | dFz7-21,... |
| Anwendung: | FZD7 receptor peptide antagonist |
| MW: | 1796 D |
ab 34,00 €