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Glepaglutide (acetate)
Artikelnummer: Cay41274-1
Glepaglutide is a peptide agonist of the glucagon-like peptide 2 receptor (GLP-2R). It selectively induces cAMP accumulation in HEK293 cells expressing GLP-2R over those expressing GLP-1R (EC50s = 0.24 and 8.7 nM, respectively, for the human receptors). Glepaglutide (10 mg/kg per day for 26 weeks) increases mucosal...
| Schlagworte: | ZP1848 |
| Anwendung: | Peptide, GLP-2R agonist |
| MW: | 4316.1 D |
ab 119,00 €
Utreglutide
Artikelnummer: Cay41275-1
Utreglutide is a G protein-biased peptide agonist of glucagon-like peptide 1 receptor (GLP-1R). It selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R over beta-arrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s = 0.63 and 79 nM, respectively). Utreglutide induces insulin...
| Schlagworte: | GL0034,... |
| Anwendung: | G-protein-biased peptide GLP-1R agonist |
| CAS | 2460862-12-6 |
| MW: | 4166.7 D |
ab 97,00 €
HOXB7 (8-25) (human)
Artikelnummer: Cay41334-1
HOXB7 (8-25) is a peptide fragment of the transcription factor homeobox protein B7 (HOXB7).Formal Name:...
| Schlagworte: | Homeobox Protein B7 (8-25),... |
| Anwendung: | HOXB7 peptide fragment |
| MW: | 1848 D |
ab 39,00 €
![Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH](https://www.biomol.com/media/image/20/78/09/Cay40707-1_200x200.png "Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH")
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH
Artikelnummer: Cay40707-1
Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide (Cay-40231, Cay-29969, Cay-40170).Formal Name:...
| Schlagworte: | Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH,... |
| Anwendung: | Semaglutide synthesis building block |
| CAS | 1662688-20-1 |
| MW: | 1196.5 D |
ab 234,00 €
Cotadutide (acetate)
Artikelnummer: Cay40714-1
Cotadutide is a synthetic peptide and dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR) that is biased toward GLP-1R. It increases cAMP accumulation in CHO cells overexpressing recombinant human GLP-1R or GCGR (EC50s = 6.9 and 10.2 pM, respectively). It also enhances...
| Schlagworte: | MEDI0382 |
| Anwendung: | GLP-1R / GCGR dual agonist, synthetic peptide |
| MW: | 3788.1 D |
ab 133,00 €
Fexapotide (trifluoroacetate)
Artikelnummer: Cay40716-10
Fexapotide (trifluoroacetate) is a peptide. It induces apoptosis in LNCaP prostate cancer cells when used at a concentration of 2.5 mg/ml. Intraprostatic administration of fexapotide triflutate (0.6 mg/animal per week) reduces the numbers of prostate glandular epithelial cells without affecting other cell types and...
| Schlagworte: | NX-1207,... |
| Anwendung: | Antineoplastic, proapoptotic peptide |
| CAS | 1609252-56-3 |
| MW: | 2625.6 D |
ab 47,00 €
GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)
Artikelnummer: Cay40718-1
Glucagon-like peptide 1 (GLP-1) (1-32) is an endogenous incretin hormone. It increases intracellular cAMP levels using HEK293 cells expressing human GLP-1 receptor (GLP-1R, EC50 = 0.051 nM). In vivo, GLP-1 (1-32) (30 mg/kg) reduces blood glucose levels in an oral glucose tolerance test (OGTT) in fasted mice.Formal...
| Schlagworte: | Glucagon-like Peptide 1 (1-32),... |
| Anwendung: | Endogenous incretin hormone |
| MW: | 3658.1 D |
ab 34,00 €
Semaglutide Side Chain
Artikelnummer: Cay40746-1
Semaglutide side chain is a synthetic intermediate. It has been used as an intermediate in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide (Cay-40231, Cay-29969, Cay-40170), as well as a lipid side chain to increase the proteolysis-resistance of insulin derivatives for use in...
| Schlagworte: | 22S-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid,... |
| Anwendung: | Synthetic intermediate |
| CAS | 1118767-16-0 |
| MW: | 846.1 D |
ab 34,00 €
(BOC-VPR)2R110
Artikelnummer: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Anwendung: | Fluorogenic alpha-thrombin substrate |
139,00 €
L-Leucyl-L-Leucine methyl ester (hydrochloride)
Artikelnummer: Cay16008-100
L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...
| Schlagworte: | LLME, LLOMe, L-leucyl-L-leucine, methyl ester, monohydrochloride |
| Anwendung: | Specific cytotoxin |
| CAS | 6491-83-4 |
| MW: | 294.8 D |
ab 43,00 €
MDM2 (32-46) (trifluoroacetate salt)
Artikelnummer: Cay38836-1
MDM2 (32-46) is a peptide fragment of MDM2. Formal Name: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-L-glutaminyl-L-lysyl-L-aspartic acid, trifluoroacetate salt. Molecular Formula: C75H135N19O20 XCF3COOH. Formula Weight: 1623.0. Purity:...
| Schlagworte: | ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-... |
| MW: | 1623 D |
ab 36,00 €
HBP08 (trifluoroacetate salt)
Artikelnummer: Cay36961-1
HBP08 is a peptide inhibitor of the protein-protein interaction between chemokine (C-X-C motif) ligand 12 (CXCL12) and high mobility group protein B1 (HMGB1). It binds to HMGB1 (Kd = 0.8 µM) and inhibits HMGB1-induced inhibition of CXCL12-induced migration of 300-19 pre-B cells expressing human chemokine (C-X-C...
| Schlagworte: | glycyl-L-tyrosyl-L-histidyl-L-tyrosyl-L-alpha-glutamyl-L-arginyl-L-tryptophyl-L-isoleucyl-L-histidine, trifluoroacetate salt |
| Anwendung: | CXCL12-HMGB1 protein-protein interaction peptide inhibitor |
| MW: | 1260.4 D |
ab 80,00 €