Peptide

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Myristoyl Hexapeptide-16 (hydrochloride)
Myristoyl Hexapeptide-16 (hydrochloride)

Artikelnummer: Cay40513-1

Myristoyl hexapeptide-16 is a myristoylated form of the hexapeptide Leu-Lys-Lys-Ala-Leu-Lys. An acid form of myristoyl hexapeptide-16 is active against E. coli, P. aeruginosa, S. aureus, and methicillin-resistant S. aureus (MRSA, MICs = =100 ppm for all).Formal Name:...
Schlagworte: Myr-Leu-Lys-Lys-Ala-Leu-Lys, tetradecanoyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-lysine, hydrochloride
Anwendung: Acylated hexapeptide
MW: 910.3 D
ab 61,00 €
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Enramycin A
Enramycin A

Artikelnummer: Cay40847-1

Enramycin A is a lipopeptide antibiotic that has been found in S. fungicidicus. It also inhibits avian myeloblastosis virus reverse transcriptase by 50% when used at a concentration of 10 µg/ml in a cell-free assay. Formulations containing enramycin A have been used as feed additives to prevent bacterial necrotic...
Schlagworte: Enduramycin A,...
Anwendung: Lipopeptide antibiotic
CAS 34438-27-2
MW: 2355.3 D
ab 47,00 €
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NEU
Mechercharmycin A
Mechercharmycin A

Artikelnummer: Cay40868-1

Mechercharmycin A is a cyclic peptide originally isolated from Thermoactinomyces that has anticancer activity. It induces cytotoxicity in A549 lung cancer and Jurkat leukemia cells (IC50s = 40 and 46 nM, respectively).Formal Name:...
Schlagworte: IB-01211,...
Anwendung: Cyclic peptide, anticancer agent
CAS 822520-96-7
MW: 708.7 D
784,00 €
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Sulfo-SMCC (sodium salt)
Sulfo-SMCC (sodium salt)

Artikelnummer: Cay35692-100

Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to...
Schlagworte: Sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate,...
Anwendung: Water-soluble protein cross-linking reagent
CAS 92921-24-9
MW: 436.4 D
ab 92,00 €
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LL-37 (13-37) (human) (trifluoroacetate salt)
LL-37 (13-37) (human) (trifluoroacetate salt)

Artikelnummer: Cay36949-1

LL-37 (13-37) is an anticancer peptide fragment of LL-37 (Cay-24461). It inhibits the ATPase activity of ATP-binding cassette transporter 2, subfamily G (ABCG2) when used at a concentration of 1 µM. LL-37 (13-37) induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-glycoprotein (P-gp), also...
Schlagworte: CAP-18, Cathelicidin, FALL-39, hCAP-18, IG-25, LL-13, LL-25,...
Anwendung: LL-37 anticancer peptide fragment
MW: 3043.6 D
ab 53,00 €
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CXCL9 (74-103) (human) (trifluoroacetate salt)
CXCL9 (74-103) (human) (trifluoroacetate salt)

Artikelnummer: Cay38849-1

Chemokine (C-X-C motif) ligand 9 (CXCL9) (74-103) is a C-terminal fragment of mature CXCL9. It binds to the glycosaminoglycan heparin in a cell-free assay (Kd = 3.1 nM). CXCL9 (74-103) inhibits the binding of CXCL8 or CXCL11 to heparin, as well as chemokine (C-C motif) ligand 2 (CCL2) binding to heparan sulfate, in...
Schlagworte: Chemokine (C-X-C motif) Ligand 9 (74-103), MIG30, Monokine Induced by Interferon-gamma (74-103)
Anwendung: CXCL9-derived peptide
MW: 3661.4 D
ab 66,00 €
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[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)
[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)

Artikelnummer: Cay39017-1

[Ala1,3,11,15]-Endothelin-1 is an endothelin receptor type B (ETB) agonist and linear synthetic peptide derivative of endothelin-1 in which all four cysteine residues have been substituted with alanine. It selectively binds to ETB over ETA receptors (IC50s = 0.33 and 570 nM, respectively, for the porcine receptors)....
Schlagworte: [Ala1,3,11,15]-ET-1, 4-Ala-ET-1,...
Anwendung: ETB receptor agonist
MW: 2367.7 D
ab 53,00 €
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Aureobasidin A
Aureobasidin A

Artikelnummer: Cay39722-10

Aureobasidin A is a cyclic depsipeptide that has been found in A. pullulans and has diverse biological activities. It inhibits inositol phosphorylceramide synthase, an enzyme involved in sphingolipid biosynthesis (Kis = 0.18 and 0.23 for the C. albicans and S. cerevisiae enzymes, respectively). Aureobasidin A also...
Schlagworte: Antibiotic R 106I, Basifungin, LY295337, NK 204, R 106-1,...
Anwendung: Bioactive cyclic depsipeptide
CAS 127785-64-2
MW: 1101.4 D
ab 218,00 €
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Retatrutide (sodium salt)
Retatrutide (sodium salt)

Artikelnummer: Cay39747-1

Retatrutide is a triple agonist of the glucagon receptor (GCGR), glucagon-like peptide 1 receptor (GLP-1R), and gastric inhibitory polypeptide receptor (GIP receptor), also known as the glucose-dependent insulinotropic polypeptide receptor. It induces cAMP accumulation in HEK293 cells expressing the human GCGR,...
Schlagworte: LY3437943,...
Anwendung: GCGR / GLP-1R / GIPR triple agonist
MW: 4731.3 D
ab 77,00 €
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PE 22-28 (acetate)
PE 22-28 (acetate)

Artikelnummer: Cay39986-1

PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin (Cay-36762). It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the...
Schlagworte: Gly-Val-Ser-Trp-Gly-Leu-Arg-OH, glycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, acetate
Anwendung: K2P2.1/TREK1 peptide inhibitor
MW: 773.9 D
ab 119,00 €
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[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate salt)
[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate...

Artikelnummer: Cay40152-1

[Asp371]-Tyrosinase (369-377) is a naturally occurring tyrosinase antigen peptide. It is formed via post-translational modification of Asn371. [Asp371]-Tyrosinase (369-377) binds to MHC class I subtype HLA-A*0201-positive T2 cells (IC50 = 1.2 µg/ml) and induces lysis of HLA-A2.1-positive T2 cells incubated with...
Schlagworte: [Asp370]-Tyrosinase (368-376), Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val,...
Anwendung: Tyrosinase antigen peptide
MW: 1031.2 D
ab 34,00 €
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Tat-Gap 19 (trifluoroacetate salt)
Tat-Gap 19 (trifluoroacetate salt)

Artikelnummer: Cay36729-1

Tat-Gap 19 is a peptide inhibitor of connexin43 (Cx43) hemichannels. It is composed of the HIV-1 Tat protein transduction domain linked to a nine-amino acid peptide corresponding to residues 128-136 of Cx43. Tat-Gap 19 (10 µM) inhibits glutamate-induced ATP release, a marker of Cx43 hemichannel activity, in primary...
Schlagworte: L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-glutami...
Anwendung: Cx43 (GJA1) hemichannel peptide inhibitor
MW: 2703.3 D
ab 155,00 €
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