MRS1523

MRS1523 is an adenosine A3 receptor antagonist. It binds to the human adenosine A3 receptor (Ki = 0.0189 µM), as well as selectively binds rat adenosine A3 over A1 and A2A receptors (Kis = 0.113, 15.6, and 2.05 µM, respectively) in radioligand binding assays. It inhibits the proliferation of B16-BL6 mouse melanoma cells when used at a concentration of 1 µM.Formal Name: 6-ethyl-5-[(ethylthio)carbonyl]-2-phenyl-4-propyl-3-pyridinecarboxylic acid propyl ester. CAS Number: 212329-37-8. Molecular Formula: C23H29NO3S. Formula Weight: 399.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml. lambdamax: 247 nm. SMILES: CCCOC(C1=C(CCC)C(C(SCC)=O)=C(CC)N=C1C2=CC=CC=C2)=O. InChi Code: InChI=1S/C23H29NO3S/c1-5-12-17-19(23(26)28-8-4)18(7-3)24-21(16-13-10-9-11-14-16)20(17)22(25)27-15-6-2/h9-11,13-14H,5-8,12,15H2,1-4H3. InChi Key: UUSHFEVEROROSP-UHFFFAOYSA-N.