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MRS1523
Artikelnummer: Cay17128-1
MRS1523 is an adenosine A3 receptor antagonist. It binds to the human adenosine A3 receptor (Ki = 0.0189 µM), as well as selectively binds rat adenosine A3 over A1 and A2A receptors (Kis = 0.113, 15.6, and 2.05 µM, respectively) in radioligand binding assays. It inhibits the proliferation of B16-BL6 mouse melanoma...
| Schlagworte: | 6-ethyl-5-[(ethylthio)carbonyl]-2-phenyl-4-propyl-3-pyridinecarboxylic acid propyl ester |
| Anwendung: | Adenosine A3 receptor agonist |
| CAS | 212329-37-8 |
| MW: | 399.5 D |
ab 87,00 €
MRS 1523
Artikelnummer: TGM-T16135-1mg
Description: MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 receptor antagonist Ki: 18.9 nM and 113 nM for human and rat A3 receptors, respectively)....
| Anwendung: | Adenosine A3 receptor agonist |
| CAS | 212329-37-8 |
| MW: | 399.55 D |
ab 187,00 €
