ML-202

ML-202 is an activator of pyruvate kinase M2 (PKM2). It induces PMK2 activation in a cell-free assay with a 50% activation concentration (AC50) value of 73 nM.Formal Name: 4,6-dihydro-6-[(3-methoxyphenyl)methyl]-4-methyl-2-(methylsulfinyl)-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one. CAS Number: 1221186-52-2. Molecular Formula: C18H17N3O3S2. Formula Weight: 387.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. lambdamax: 270, 305 nm. SMILES: O=C1C2=C(C3=C(N2C)C=C(S(C)=O)S3)C=NN1CC4=CC(OC)=CC=C4. InChi Code: InChI=1S/C18H17N3O3S2/c1-20-14-8-15(26(3)23)25-17(14)13-9-19-21(18(22)16(13)20)10-11-5-4-6-12(7-11)24-2/h4-9H,10H2,1-3H3. InChi Key: MORBXZMIXGYQDB-UHFFFAOYSA-N.