Zu "K00873" wurden 190 Artikel gefunden!
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NEU
PKM1 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-07217-10ug
Description: PKM1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is P52480.
| Schlagworte: | Pkm , Pkm2 , Pk-3 , Pk3 , Pykm , Pk-2 |
| MW: | 60.25 kD |
ab 72,00 €
PKM2, His, Mouse
Artikelnummer: GSC-Z06313-100
Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, is a critical regulator in tumor metabolism. PKM2 has been demonstrated to overexpressed in various cancers and promoted proliferation and metastasis of tumor cells.
| Schlagworte: | Pkm, Pyruvate kinase PKM, Tyrosine-protein kinase PKM2, Threonine-protein kinase PKM2, Pyruvate kinase muscle isozyme |
| Ursprungsart: | mouse |
| MW: | 58.95 kD |
ab 497,00 €
ML-265
Artikelnummer: Cay13942-10
Pyruvate kinase catalyzes the final step in glycolysis, the formation of pyruvate and ATP from phosphoenolpyruvate and ADP. The expression of the M2 isozyme of pyruvate kinase (PKM2) plays an important role in the metabolic reprogramming of tumor cells, which require high amounts of glucose for proliferation. PKM2...
| Schlagworte: | CID-44246499, NCGC00186528, TEPP-46,... |
| Anwendung: | PKM2 activator |
| CAS | 1221186-53-3 |
| MW: | 372.5 D |
ab 40,00 €
DASA-58
Artikelnummer: Cay13941-10
DASA-58 is a selective activator of pyruvate kinase M2 (PKM2, AC50 = 38 nM in vitro, EC50 = 19.6 µM in cells). DASA-58 converts PKM2 to a constitutively active enzyme state that is resistant to inhibition by tyrosine-phosphorylated proteins. Through its effects on PKM2, DASA-58 blocks the induction of HIF-1alpha by...
| Schlagworte: | ML-203, NCGC00185916, 3-[[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]hexahydro-1H-1,4-diazepin-1-yl]sulfonyl]-benzenamine |
| Anwendung: | PKM2 activator |
| CAS | 1203494-49-8 |
| MW: | 453.5 D |
ab 67,00 €
Anti-PKM2
Artikelnummer: A303-659A
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric...
| Schlagworte: | Anti-p58, Anti-PKM, Anti-OIP3, Anti-OIP-3, Anti-CTHBP, Anti-THBP1, EC=2.7.1.40, Anti-Tumor M2-PK, Anti-Pyruvate kinase... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
PKM2 (PKM2/Variant 1), His-tag
Artikelnummer: BPS-50295
Active human Pyruvate kinase M2 (PKM2) (GenBank Accession No. NM_002654) full length with N-terminal His tag, MW = 58.9 kDa, expressed in an E. coli expression system.
| Schlagworte: | p58, PKM, THBP1, CTHBP, OIP-3, Tumor M2-PK, Pyruvate kinase PKM, Pyruvate kinase 2/3, Opa-interacting protein 3,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 58.9 kD |
760,00 €
Anti-PKM2
Artikelnummer: E-AB-13771.20
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor...
| Schlagworte: | Anti-p58, Anti-PKM, Anti-OIP3, Anti-CTHBP, Anti-OIP-3, Anti-THBP1, EC=2.7.1.40, Anti-Tumor M2-PK, Anti-Pyruvate kinase... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
TEPP-46
Artikelnummer: TGM-T7214-1mg
Description: TEPP-46 (ML265) is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. . Target: PKM. Smiles: Cn1c2cc(sc2c2cnn(Cc3cccc(N)c3)c(=O)c12)S(C)=O. References: Walsh M J , Brimacombe K R...
| Schlagworte: | ML265 |
| Anwendung: | PKM2 activator |
| CAS | 1221186-53-3 |
| MW: | 372.46 D |
ab 39,00 €
Anti-PKM1/2
Artikelnummer: ARG51336.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric...
| Schlagworte: | Anti-p58, Anti-PKM, Anti-OIP3, Anti-THBP1, Anti-CTHBP, Anti-OIP-3, EC=2.7.1.40, Anti-Tumor M2-PK, Anti-Pyruvate kinase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-PKM2
Artikelnummer: ARG51403.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric...
| Schlagworte: | Anti-p58, Anti-PKM, Anti-OIP3, Anti-THBP1, Anti-CTHBP, Anti-OIP-3, EC=2.7.1.40, Anti-Tumor M2-PK, Anti-Pyruvate kinase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-phospho-PKM2 (Ser37)
Artikelnummer: ARG51804.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric...
| Schlagworte: | Anti-phospho-PKM, Anti-phospho-p58, Anti-phospho-OIP3, Anti-phospho-OIP-3, Anti-phospho-CTHBP, Anti-phospho-THBP1,... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-PKM2, clone 1A7-G6-H6
Artikelnummer: ARG55901.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric...
| Schlagworte: | Anti-p58, Anti-PKM, Anti-OIP3, Anti-OIP-3, Anti-CTHBP, Anti-THBP1, Anti-Tumor M2-PK, EC=2.7.1.40, Anti-Pyruvate kinase... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
658,00 €