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EP2 Receptor (rat) Reporter Assay Kit
Artikelnummer: Cay600340-1
The EP2 receptor is one of four GPCRs that mediate the actions of PGE2. The diverse effects of PGE2 acting via EP2 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases. Cayman's EP2...
| Schlagworte: | PGE2 Receptor 2, Prostaglandin E2 Receptor 2 |
| Anwendung: | Reverse transfection reporter assay |
| Spezies-Reaktivität: | rat |
621,00 €
CYP2C9 Induction Reporter Assay Kit
Artikelnummer: Cay601120-1
Early screening of drug candidate's potential to induce or inhibit CYP2C9 is a critical step in the drug development process. The CYP2C9 Induction Reporter Assay Kit is a novel method to evaluate CYP2C9 induction by drug candidates. Cayman's CYP2C9 Induction Reporter Assay Kit consists of a 96-well plate coated with...
| Schlagworte: | CYP2C9, CYP2C10, CYPIIC9, EC=1.14.13.-, EC=1.14.13.48, EC=1.14.13.80, EC=1.14.13.49, Cytochrome P-450MP, Cytochrome P450... |
| Anwendung: | Reverse transfection reporter assay |
621,00 €
PPARgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00102
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
| Schlagworte: | NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
PPARalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00112
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
| Schlagworte: | NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
PPARdelta (human) Reporter Assay Kit
Artikelnummer: IB-IB00122
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
| Schlagworte: | NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
LXR (human) Reporter Assays Panel
Artikelnummer: IB-IB00321-48P
INDIGO's panel of LXR Assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (NR1H3) and beta (NR1H2), ligand-dependent transcription factors commonly referred to as LXRalpha and LXRbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to an...
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.894,00 €
ERbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00412
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
ER (human) Reporter Assays Panel
Artikelnummer: IB-IB00421-48P
INDIGO's panel of ER assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (ER1, NR3A1) and beta (ER2, NR3A2), ligand-dependent transcription factors commonly referred to as ERalpha and ERbeta. INDIGO's ER reporter cells include the luciferase reporter gene functionally...
| Schlagworte: | estrogen receptor alpha, ER1, NR3A1, estrogen receptor beta, ER2, NR3A2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.894,00 €
VDR (human) Reporter Assay Kit
Artikelnummer: IB-IB00702
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human vitamin D receptor (NR1I1), a ligand-dependent transcription factor commonly referred to as VDR. INDIGO's reporter cells include the luciferase reporter gene functionally linked...
| Schlagworte: | VDR, NR1I1, Vitamin D3 receptor, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
RXRalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00802
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
RXRbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00812
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
RXRgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00822
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €