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One-Step Luciferase Assay System
Artikelnummer: BPS-60690-1
The One-Step Luciferase Assay System is designed to be used for high-throughput, sensitive quantitation of firefly luciferase activity in mammalian cell culture. The reagent consists of two components, a Luciferase Reagent Buffer (Component A) and Luciferase Reagent Substrate (Component B). Component A and Component...
| Schlagworte: | Luciferin, Firefly luciferase, luciferase buffer, |
| Anwendung: | Firefly luciferase assays, HTS |
ab 265,00 €
AR (human) Reporter Assay Kit
Artikelnummer: IB-IB03001
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
RORgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB04001
This human RAR-related orphan receptor gamma (RORgamma) mRNA is expressed from the RORC gene in two forms via alternate usage of tissue-specific promoters. Variant 1 mRNA is expressed in numerous tissues, and encodes receptor isoform 1, referred to as RORgamma. Variant 2 mRNA comprises an alternate exon 1 that...
| Schlagworte: | RORC, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan receptor C, Retinoid-related... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
Human GHR Reporter Assay System
Artikelnummer: IB-IB14001
The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
| Schlagworte: | GHR |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Human |
ab 1.588,00 €
Reporter Assay Panel for Calcitonin and Amylin Receptors
Artikelnummer: Cay502933-1
Cayman's reverse transfection reporter assays have overcome many of the disadvantages of other transfection approaches. In this method, a proprietary transfection complex containing DNA and an optimized mixture of lipids and proteins has been evenly applied and processed on the culture surface of multi-well plates....
| Schlagworte: | CTR/AMYR |
| Anwendung: | Cell-based secreted alkaline phosphatase reporter assay panel |
| Spezies-Reaktivität: | human |
832,00 €
Elk-1 Reporter Assay System (human)
Artikelnummer: IB-IB22111
Protein Function: Transcription factor that binds to purine-rich DNA sequences (PubMed:10799319, PubMed:7889942). Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (PubMed:1630903). Induces target gene...
| Schlagworte: | ELK1, ETS domain-containing protein Elk-1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
PDGFRbeta Inhibition Reporter Assay System (human)
Artikelnummer: IB-IB23201
Protein Function: Tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an...
| Schlagworte: | PDGFRB, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, Beta platelet-derived growth factor... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
GIPR Inhibition Reporter Assay System (human)
Artikelnummer: IB-IB38101
Protein Function: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase [The Uniprot Consortium]
| Schlagworte: | GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
MC3R Reporter Assay System (human)
Artikelnummer: IB-IB41301
Protein Function: Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (By similarity). Induces target gene transcription upon JNK and...
| Schlagworte: | Elk1, ETS domain-containing protein Elk-1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
MC4R Reporter Assay System (human)
Artikelnummer: IB-IB41401
Protein Function: Hormone receptor that acts as a key component of the leptin-melanocortin pathway at the intersection of homeostatic maintenance of energetic state (PubMed:32327598, PubMed:33858992). Plays a role in regulating food intake: activation by a stimulating hormone such as anorexigenic alpha-melanocyte...
| Schlagworte: | MC4R, Melanocortin receptor 4 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
MC5R Reporter Assay System (human)
Artikelnummer: IB-IB41501
Protein Function: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins [The Uniprot Consortium]
| Schlagworte: | MC-2, MC5R, Melanocortin receptor 5 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
AMY1R Reporter Assay System (human)
Artikelnummer: IB-IB48101
Protein Function: Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:33602864, PubMed:9620797, PubMed:35324283, PubMed:38603770). Required for the transport of...
| Schlagworte: | RAMP1, Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €