Reporter-Assays

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AR (human) Reporter Assay Kit
AR (human) Reporter Assay Kit

Artikelnummer: IB-IB03001-32

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Schlagworte: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.068,00 €
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Melanocortin-3 Receptor Reporter Assay Kit
Melanocortin-3 Receptor Reporter Assay Kit

Artikelnummer: Cay600180-100

The Melanocortin-3 receptor (MC3R) helps regulate energy homeostasis and mice lacking MC3R have increased fat mass and reduced lean mass. Therefore, agonists that selectively activate MC3R might have beneficial effects related to weight gain and glucose metabolism. This assay consists of a 96-well plate coated with...
Anwendung: Reverse transfection reporter assay
500,00 €
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Melanocortin-4 Receptor Reporter Assay Kit
Melanocortin-4 Receptor Reporter Assay Kit

Artikelnummer: Cay600190-100

The melanocortin-4 receptor (MC4R) has important roles in weight regulation, sexual function, and inflammation. Mice deficient in MC4R have increased lipid deposition associated with elevated adiposity, while mutations in MC4R in humans are associated with early onset or severe obesity. This assay consists of a...
Anwendung: Reverse transfection reporter assay
500,00 €
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Orexin Receptor 1 STEP(TM) Reporter Assay Kit (Luminescence)
Orexin Receptor 1 STEP(TM) Reporter Assay Kit...

Artikelnummer: Cay600240-100

Surface Transfection and Expression Protocol (STEP(TM)) is a novel, patented, solid phase transient transfection technology that overcomes many of the disadvantages of other transfection approaches. CaymansOrexin 1 Receptor (OX1R) STEP(TM) Reporter Assay Kit (Luminescence) consists of a 96-well plate coated with...
Schlagworte: Ox1R, Ox1-R, Ox-1-R, HCRTR1, Orexin receptor type 1, Hypocretin receptor type 1
Anwendung: OX1R activation assays
500,00 €
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Orexin 2 Receptor Reporter Assay Kit
Orexin 2 Receptor Reporter Assay Kit

Artikelnummer: Cay600250-100

Surface Transfection and Expression Protocol (STEP(TM)) is a novel, patented, solid phase transient transfection technology that overcomes many of the disadvantages of other transfection approaches. CaymansOrexin 2 Receptor (OX2R) STEP(TM) Reporter Assay Kit (Luminescence) consists of a 96-well plate coated with...
Schlagworte: Ox2R, Ox2-R, Ox-2-R, HCRTR2, Orexin receptor type 2, Hypocretin receptor type 2
Anwendung: OX2R activation assays
500,00 €
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Secreted Alkaline Phosphatase Reporter Gene Assay Kit (Luminescence)
Secreted Alkaline Phosphatase Reporter Gene...

Artikelnummer: Cay600260-300

Secreted alkaline phosphatase (SEAP) is commonly used as a reporter of gene expression. Compared to other conventional intracellular reporters such as chloramphenicol acetyltransferase (CAT) and firefly luciferase, SEAP has the advantage of being secreted from transfected cells into the culture medium. Cayman's...
Schlagworte: SEAP Reporter Gene
Anwendung: Chemiluminescence
287,00 €
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EP2 Receptor (rat) Reporter Assay Kit
EP2 Receptor (rat) Reporter Assay Kit

Artikelnummer: Cay600340-1

The EP2 receptor is one of four GPCRs that mediate the actions of PGE2. The diverse effects of PGE2 acting via EP2 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases. Cayman's EP2...
Schlagworte: Ptger2, Prostanoid EP2 receptor, PGE receptor EP2 subtype, PGE2 receptor EP2 subtype, Prostaglandin E2 receptor EP2 subtype
Anwendung: Reverse transfection reporter assay
Reaktivität: Rat
500,00 €
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EP4 Receptor (rat) Reporter Assay Kit
EP4 Receptor (rat) Reporter Assay Kit

Artikelnummer: Cay600350-100

The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various...
Schlagworte: Ptger4, Prostanoid EP4 receptor, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E2 receptor EP4 subtype
Anwendung: Reverse transfection reporter assay
Reaktivität: Rat
500,00 €
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CYP1A1/2 Induction Reporter Assay Kit
CYP1A1/2 Induction Reporter Assay Kit

Artikelnummer: Cay600670-100

Early screening of a drug candidate's potential to induce or inhibit CYP1A1/2 is a critical step in the drug development process. Cayman's CYP1A1/2 Induction Reporter Assay Kit is a novel method to assess CYP1A2 induction. Our Reverse Transfection Reporter Assays have overcome many of the disadvantages of other...
Schlagworte: CYP1A1/2 Induction STEP Reporter Assay Kit (Luminescence)
Anwendung: Reverse transfection reporter assay
500,00 €
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CYP2B6 Induction Reporter Assay Kit
CYP2B6 Induction Reporter Assay Kit

Artikelnummer: Cay600680-100

Early screening of a drug candidate's potential to induce or inhibit CYP2B6 is a critical step in the drug development process. Cayman's CYP2B6 Induction Reporter Assay Kit is a novel method to evaluate human Constitutive Androstane Receptor 3 (hCAR3)-mediated CYP2B6 induction for the discovery of hepatic CYP...
Schlagworte: CYP2B6 Induction STEP Reporter Assay Kit (Luminescence)
Anwendung: Reverse transfection reporter assay
500,00 €
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CYP2C9 Induction Reporter Assay Kit
CYP2C9 Induction Reporter Assay Kit

Artikelnummer: Cay601120-1

Early screening of drug candidate's potential to induce or inhibit CYP2C9 is a critical step in the drug development process. The CYP2C9 Induction Reporter Assay Kit is a novel method to evaluate CYP2C9 induction by drug candidates. Cayman's CYP2C9 Induction Reporter Assay Kit consists of a 96-well plate coated with...
Schlagworte: CYP2C9, CYP2C10, CYPIIC9, EC=1.14.13.-, EC=1.14.13.48, EC=1.14.13.80, EC=1.14.13.49, Cytochrome P-450MP, Cytochrome P450...
Anwendung: Reverse transfection reporter assay
500,00 €
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FFAR1 (GPR40) Reporter Assay Kit
FFAR1 (GPR40) Reporter Assay Kit

Artikelnummer: Cay601190-1

Free fatty acid receptor 1 (FFAR1)/GPR40 is a G protein-coupled receptor for long-chain fatty acids such as docosahexaenoic acid and eicosapentaenoic acid omega-3 fatty acids. It is involved in the regulation of insulin release from pancreatic beta cells and mediates triglyceride-induced secretion of incretins GLP-1...
Schlagworte: Free Fatty Acid Receptor 1, G Protein-Coupled Receptor 40
Anwendung: Cell based assays, HTS, Reverse transfection reporter assay
Reaktivität: Human
500,00 €
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