Reporter-Assays

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Secreted Alkaline Phosphatase Reporter Gene Assay Kit (Luminescence)
Secreted Alkaline Phosphatase Reporter Gene Assay Kit...

Artikelnummer: Cay600260-300

Secreted alkaline phosphatase (SEAP) is commonly used as a reporter of gene expression. Compared to other conventional intracellular reporters such as chloramphenicol acetyltransferase (CAT) and firefly luciferase, SEAP has the advantage of being secreted from transfected cells into the culture medium. Cayman's...
Schlagworte: SEAP Reporter Gene
Anwendung: Chemiluminescence
287,00 €
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One-Step Luciferase Assay System
One-Step Luciferase Assay System

Artikelnummer: BPS-60690-1

The One-Step Luciferase Assay System is designed to be used for high-throughput, sensitive quantitation of firefly luciferase activity in mammalian cell culture. The reagent consists of two components, a Luciferase Reagent Buffer (Component A) and Luciferase Reagent Substrate (Component B). Component A and Component...
Anwendung: Firefly luciferase assays, HTS
ab 171,00 €
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AR (human) Reporter Assay Kit
AR (human) Reporter Assay Kit

Artikelnummer: IB-IB03001

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Schlagworte: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
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Notch Reporter Assay Kit (cAMP/PKA pathway)
Notch Reporter Assay Kit (cAMP/PKA pathway)

Artikelnummer: BPS-60509

Notch Pathway Reporter kit is designed for monitoring the activity of Notch signaling pathway in the cultured cells. The kit contains the transfection-ready Notch1 NICD expression vector and CSL (CBF1/RBP-Jkappa) luciferase reporter vector, which is a Notch pathway-responsive reporter. This reporter contains a...
Anwendung: Notch activity assays
743,00 €
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WNT TCF/LEF reporter kit
WNT TCF/LEF reporter kit

Artikelnummer: BPS-60500

The TCF/LEF Reporter kit is designed for monitoring the activity of Wnt / b-catenin signaling pathway in the cultured cells. The kit contains transfection-ready TCF/LEF luciferase reporter vector, which is a Wnt pathway- responsive reporter. This reporter contains a firefly luciferase gene under the control of...
Schlagworte: LEF1, LEF-1, TCF1-alpha, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha reporter
Anwendung: Wnt pathway activation assays, TCF/LEF reporter assay
Reaktivität: Human
712,00 €
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RORgamma (human) Reporter Assay Kit
RORgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB04001

This human RAR-related orphan receptor gamma (RORgamma) mRNA is expressed from the RORC gene in two forms via alternate usage of tissue-specific promoters. Variant 1 mRNA is expressed in numerous tissues, and encodes receptor isoform 1, referred to as RORgamma. Variant 2 mRNA comprises an alternate exon 1 that...
Schlagworte: RORC, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan receptor C, Retinoid-related...
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
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ERalpha (human) Reporter Assay Kit
ERalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00401

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
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PXR (human) Reporter Assay Kit
PXR (human) Reporter Assay Kit

Artikelnummer: IB-IB07001

Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the...
Schlagworte: SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic...
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
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RARbeta (human) Reporter Assay Kit
RARbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB02101

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor, beta (NR1B2), a ligand-dependent transcription factor commonly referred to as RARB or RARbeta. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: HAP, RARB, RAR-beta, RAR-epsilon, HBV-activated protein, Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B...
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
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SRE Reporter Kit (MAPK/ERK Signaling Pathway )
SRE Reporter Kit (MAPK/ERK Signaling Pathway )

Artikelnummer: BPS-60511

The MAPK/ERK signaling pathway is a major participant in the regulation of cell growth and differentiation. It can be activated by various extracellular stimuli including mitogens, growth factors, and cytokines. Upon stimulation, MEK1/2 phosphorylate and activate ERK1/2. The activated ERK translocates to the nucleus...
Anwendung: MAPK/ERK signaling pathway assays
712,00 €
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ARE Reporter Kit (Nrf2 Antioxidant Pathway )
ARE Reporter Kit (Nrf2 Antioxidant Pathway )

Artikelnummer: BPS-60514

The ARE Reporter kit is designed for monitoring the activity of the Nrf2 antioxidant pathway in cultured cells. The kit contains a transfection-ready ARE luciferase reporter vector, which is an Nrf2 pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized ARE...
Schlagworte: NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor, erythroid derived 2, like 2, Nuclear...
Anwendung: Nrf2 pathway activity studies, Activator/inhibitor screening
743,00 €
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RORa (Human) Reporter Assay System
RORa (Human) Reporter Assay System

Artikelnummer: IB-IB04011-32

Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid,...
Schlagworte: RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related...
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
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