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Artikelnummer: IB-IB03002
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
3.802,00 €
Artikelnummer: IB-IB00201
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human glucocorticoid receptor (NR3C1), a ligand-dependent transcription factor, commonly referred to as GR. INDIGO's reporter cells include the luciferase...
Schlagworte: | GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1 |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
ab 1.448,00 €
Artikelnummer: IB-M04001
Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and...
Schlagworte: | TOR, Rorc, Nr1f3, Thymus orphan receptor, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan... |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | mouse |
ab 1.448,00 €
Artikelnummer: ABD-12518
Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase. The advantages of a luciferase assay are the high sensitivity, the absence of luciferase activity inside most of the cell types, the wide dynamic range, rapidity and low cost. The most versatile and common reporter gene is the...
Schlagworte: | Luciferase assays, HTS |
Anwendung: | Bioluminescence assays, Luciferase assays |
ab 208,00 €
Artikelnummer: IB-MR00101
This nuclear receptor assay system utilizes a proprietary rodent cell line that is further engineered to express the mouse/rat peroxisome proliferator-activated receptor gamma (NR1C3, PPARG). Because the receptor's ligand binding domain sequence is conserved between mouse and rat species, the receptor is denoted...
Schlagworte: | Nr1c3, Pparg, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | mouse, rat |
ab 1.448,00 €
Artikelnummer: BPS-79322
The RARalpha Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor alpha (RARalpha). The pack contains the RARalpha Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic...
Schlagworte: | RAR Alpha, NCOR2, SMRT, RARA, Retinoic Acid Receptor Alpha, |
Anwendung: | Pathway monitoring, agonist/antagonist screening |
Spezies-Reaktivität: | human |
3.397,00 €
Artikelnummer: BPS-79323
The RARbeta Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor beta (RARbeta). The pack contains theRARbeta Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic acid...
Schlagworte: | RAR Beta, Retinoic Acid Receptor Beta, RARB, |
Anwendung: | Pathway monitoring, agonist/antagonist screening |
Spezies-Reaktivität: | human |
2.933,00 €
Artikelnummer: BPS-79324
The RARgamma Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor gamma (RARgamma). The pack contains the RARgamma Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic...
Schlagworte: | RAR Gamma, Retinoic Acid Receptor Gamma, RARG, |
Anwendung: | Pathway monitoring, agonist/antagonist screening |
Spezies-Reaktivität: | human |
2.933,00 €
Artikelnummer: BPS-79325
The NF-kappaB Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of the nuclear factor Kappa B (NF-kappaB) signal transduction pathways. The pack contains the NF-kappaB Reporter (Luc)- CHO-K1 Recombinant Cell Line, a luciferase reporter cell line that contains a firefly...
Schlagworte: | NF-kappaB Cell Line, NFkappaB Cell Line, Luciferase Reporter, NF-kB Cell Line, NFkB Cell Line, |
Anwendung: | Pathway monitoring, inhibitor screening |
Spezies-Reaktivität: | human |
1.809,00 €
Artikelnummer: BPS-79326
The NF-kappaB Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of the nuclear factor Kappa B (NF-kappaB) signal transduction pathways. The pack contains the NF-kappaB Reporter (Luc)- HCT-116 Recombinant Cell Line, a luciferase reporter cell line that contains a firefly...
Schlagworte: | NF-kappaB Cell Line, NFkappaB Cell Line, Luciferase Reporter, NF-kB Cell Line, NFkB Cell Line, |
Anwendung: | Pathway monitoring, inhibitor screening |
Spezies-Reaktivität: | human |
1.809,00 €
Artikelnummer: BPS-79327
The NF-kappaB Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of the nuclear factor Kappa B (NF-kappaB) signal transduction pathways. The pack contains the NF-kappaB Reporter (Luc)-HEK293 Recombinant Cell Line, a luciferase reporter cell line that contains a firefly...
Schlagworte: | NF-kappaB Cell Line, NFkappaB Cell Line, Luciferase Reporter, NF-kB Cell Line, NFkB Cell Line, |
Anwendung: | Pathway monitoring, inhibitor screening |
Spezies-Reaktivität: | human |
2.190,00 €
Artikelnummer: BPS-79379
The CSF1R SRE Reporter Kit is designed for monitoring the activity of the CSF1R signaling pathway in cultured cells. The kit contains a transfection-ready vector for CSF1R and SRE luciferase reporter vector. Upon ligand binding, active CSF1R will initiate the MAPK/ERK signaling pathway, leading to expression of the...
Schlagworte: | FMS, CD115, |
Anwendung: | Signaling pathway monitoring, , activator/inhibitor screening, RNAi / gene overexpression studies |
Spezies-Reaktivität: | human |
905,00 €