Für die Filterung wurden keine Ergebnisse gefunden!
Human M-CSFR Reporter Assay System
Artikelnummer: IB-IB30202
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Schlagworte: | Anti-FMS, Anti-CSF1R, Anti-CD115, Anti-CSF-1R, Anti-CSF-1-R, Anti-M-CSF-R, EC=2.7.10.1, Anti-CSF-1 receptor,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
WNT TCF/LEF reporter kit
Artikelnummer: BPS-60500
The TCF/LEF Reporter kit is designed for monitoring the activity of Wnt / b-catenin signaling pathway in the cultured cells. The kit contains transfection-ready TCF/LEF luciferase reporter vector, which is a Wnt pathway- responsive reporter. This reporter contains a firefly luciferase gene under the control of...
| Schlagworte: | WNT reporter, TCF reporter, LEF reporter, luciferase reporter, |
| Anwendung: | Wnt pathway activation assays, TCF/LEF reporter assay |
| Spezies-Reaktivität: | human |
963,00 €
Notch Reporter Assay Kit (cAMP/PKA pathway)
Artikelnummer: BPS-60509
Notch Pathway Reporter kit is designed for monitoring the activity of Notch signaling pathway in the cultured cells. The kit contains the transfection-ready Notch1 NICD expression vector and CSL (CBF1/RBP-Jkappa) luciferase reporter vector, which is a Notch pathway-responsive reporter. This reporter contains a...
| Schlagworte: | Notch reporter, PKA reporter, cAMP reporter, luciferase reporter , CSL reporter, CBF1 reporter, RBP-J reporter, |
| Anwendung: | Notch activity assays |
869,00 €
Secreted Alkaline Phosphatase Reporter Gene Assay Kit...
Artikelnummer: Cay600260-300
Secreted alkaline phosphatase (SEAP) is commonly used as a reporter of gene expression. Compared to other conventional intracellular reporters such as chloramphenicol acetyltransferase (CAT) and firefly luciferase, SEAP has the advantage of being secreted from transfected cells into the culture medium. Cayman's...
| Schlagworte: | SEAP Reporter Gene |
| Anwendung: | Chemiluminescence |
358,00 €
PPARgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00101
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
| Schlagworte: | NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
FFAR1 (GPR40) Reporter Assay Kit
Artikelnummer: Cay601190-1
Free fatty acid receptor 1 (FFAR1)/GPR40 is a G protein-coupled receptor for long-chain fatty acids such as docosahexaenoic acid and eicosapentaenoic acid omega-3 fatty acids. It is involved in the regulation of insulin release from pancreatic beta cells and mediates triglyceride-induced secretion of incretins GLP-1...
| Schlagworte: | Free Fatty Acid Receptor 1, G Protein-Coupled Receptor 40 |
| Anwendung: | Cell based assays, HTS, reverse transfection reporter assay |
| Spezies-Reaktivität: | human |
621,00 €
Myc Reporter Kit (Myc Signaling Pathway)
Artikelnummer: BPS-60519
The Myc Pathway Reporter kit is designed for monitoring the activity of the Myc signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for c- Myc and Myc luciferase reporter vector. Inside the cells, c-Myc will bind to Max, translocate to the nucleus, and induce expression of...
| Schlagworte: | MYC, BHLHE39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, Myc proto-oncogene protein, Class E basic... |
| Anwendung: | Myc signaling pathway activity monitoring, activator screening |
| Spezies-Reaktivität: | human |
920,00 €
ARE Reporter Kit (Nrf2 Antioxidant Pathway )
Artikelnummer: BPS-60514
The ARE Reporter kit is designed for monitoring the activity of the Nrf2 antioxidant pathway in cultured cells. The kit contains a transfection-ready ARE luciferase reporter vector, which is an Nrf2 pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized ARE...
| Schlagworte: | HEBP1, Nrf-2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor,... |
| Anwendung: | Nrf2 pathway activity studies, activator/inhibitor screening |
956,00 €
ERalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00401
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
Nrf2 (Human) Reporter Assay System
Artikelnummer: IB-IB10001
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
PPARalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
| Schlagworte: | NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
SRE Reporter Kit (MAPK/ERK Signaling Pathway )
Artikelnummer: BPS-60511
The MAPK/ERK signaling pathway is a major participant in the regulation of cell growth and differentiation. It can be activated by various extracellular stimuli including mitogens, growth factors, and cytokines. Upon stimulation, MEK1/2 phosphorylate and activate ERK1/2. The activated ERK translocates to the nucleus...
| Schlagworte: | SRE reporter, MAPK reporter, ERK reporter, |
| Anwendung: | MAPK/ERK signaling pathway assays |
876,00 €