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FOXO Reporter Kit (PI3K/AKT Signaling Pathway)
Artikelnummer: BPS-60643
The FOXO Reporter kit is designed to monitor activity of the PI3K/AKT signaling pathway and the transcriptional activity of FOXO proteins in cultured cells. The kit contains the transfection-ready FOXO3 expression vector and the FOXO luciferase reporter vector, which is a PI3K/Akt pathway-responsive reporter. This...
| Schlagworte: | FOXO reporter, forkhead reporter, PI3K reporter, AKT reporter, FOXO1 reporter, FOXO3 reporter, FOXO4 reporter, |
| Anwendung: | PI3K/AKT pathway monitoring |
832,00 €
TGR5 (GP-BAR1) Reporter Assay Kit
Artikelnummer: Cay601440-1
Bile acids are a diverse class of amphipathic molecules originally formed in liver and modified by microorganisms in the intestine. In addition to their conventional role in dietary lipid absorption, bile acids have been recognized as signaling molecules that regulate the synthesis and metabolism of bile acids,...
| Schlagworte: | BG37, TGR5, M-BAR, hBG37, GPBAR1, hGPCR19, G-protein coupled receptor GPCR19, Membrane-type receptor for bile acids,... |
| Anwendung: | Cell based assays, HTS, reverse transfection reporter assay |
621,00 €
PPAR (human) Reporter Assays Panel
Artikelnummer: IB-IB00131-32P
INDIGO's panel of PPAR reporter assays utilizes non-human mammalian cells engineered to express human peroxisome proliferator-activated receptors: PPARalpha (NR1C1), PPARdelta (NR1C2), or PPARgamma (NR1C3), all ligand-dependent transcription factors that are commonly referred to as PPARalpha, PPARdelta and...
| Schlagworte: | PPARalpha (NR1C1), PPARdelta (NR1C2), PPARgamma (NR1C3) |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.894,00 €
LXRbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00302
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human liver X receptor beta (NR1H2), a ligand-dependent transcription factor commonly referred to as LXRbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | LXRB, NR1H2, Nuclear receptor NER, Liver X receptor beta, Oxysterols receptor LXR-beta, Ubiquitously-expressed nuclear... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
MR (human) Reporter Assay Kit
Artikelnummer: IB-IB00502
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
FXR (human) Reporter Assay Kit
Artikelnummer: IB-IB00602
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
PR (human) Reporter Assay Kit
Artikelnummer: IB-IB05002
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the full-length human progesterone receptor (NR3C3), a ligand-dependent transcription factor commonly referred to as PR. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
MR (human) Reporter Assay Kit
Artikelnummer: IB-IB00501-32
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
PPARdelta (human) Reporter Assay Kit
Artikelnummer: IB-IB00121
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
| Schlagworte: | NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
FXR (mouse) Reporter Assay Kit
Artikelnummer: IB-M00601-32
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | Bar, Nr1h4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
ab 1.448,00 €
Amplite(TM) Gaussia Luciferase Reporter Gene Assay Kit...
Artikelnummer: ABD-12530
Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase. The most versatile reporter gene is the firefly luciferase. Recently there is steadily increasing use of other luciferases, such as Gaussia luciferase since these reporters are smaller and do not require the presence of ATP. The...
| Anwendung: | Gaussia Luciferase assay |
ab 279,00 €
AP1 Reporter Kit (JNK Pathway)
Artikelnummer: BPS-60612
The AP1 Reporter Kit is designed for monitoring the activity of the JNK signaling pathway and the transcriptional activity of AP1 in cultured cells. The kit contains a transfection-ready AP1 luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized AP1...
| Schlagworte: | JNK reporter, SAPK reporter, |
| Anwendung: | JNK activity assays |
832,00 €