Zell-basierte Assays

In der modernen Life Science und Pharmaforschung gewinnen Zell-basierte Assays immer mehr an Bedeutung. Echtzeitmessungen mit Zellen bieten die Möglichkeit der erfolgreichen Quantifizierung von Zellviabilität, Zytotoxizität und biologischer Aktivität. Da sie die Situation in vivo realitätsnah darstellen, ermöglichen diese Assays eine direkte Analyse von Zellreaktionen und spielen unter anderem eine wichtige Rolle für das Verständnis von Krankheitsmechanismen.

In der modernen Life Science und Pharmaforschung gewinnen Zell-basierte Assays immer mehr an Bedeutung. Echtzeitmessungen mit Zellen bieten die Möglichkeit der erfolgreichen Quantifizierung von... mehr erfahren »
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Zell-basierte Assays

In der modernen Life Science und Pharmaforschung gewinnen Zell-basierte Assays immer mehr an Bedeutung. Echtzeitmessungen mit Zellen bieten die Möglichkeit der erfolgreichen Quantifizierung von Zellviabilität, Zytotoxizität und biologischer Aktivität. Da sie die Situation in vivo realitätsnah darstellen, ermöglichen diese Assays eine direkte Analyse von Zellreaktionen und spielen unter anderem eine wichtige Rolle für das Verständnis von Krankheitsmechanismen.

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Annexin V-iFluor 488 + PI Apoptosis Detection Reagent
Annexin V-iFluor 488 + PI Apoptosis Detection Reagent

Artikelnummer: CR-C08006-K01

Croyez fluorescent dye (iFluor 488) conjugated Annexin V is highly purified product. During early apoptosis, cells will translocate membrane phosphatidylserine (PS) from the inner face of the membrane to the cell surface. Propidium iodide (PI) is a common fluorescent dye to detect DNA. It can be used in flow...
ab 120,00 €
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Annexin V-FAM + 7-AAD Apoptosis Detection Reagent
Annexin V-FAM + 7-AAD Apoptosis Detection Reagent

Artikelnummer: CR-C08008-K01

Croyez fluorescent dye (FAM) conjugated Annexin V is highly purified product. During early apoptosis, cells will translocate membrane phosphatidylserine (PS) from the inner face of the membrane to the cell surface. 7-Aminoactinomycin D (7-AAD) is a fluorescent chemical compound with a strong affinity for DNA. It can...
300,00 €
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Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit * Blue Fluorescence*
Cell Meter(TM) Caspase 3/7 Activity Apoptosis Assay Kit *...

Artikelnummer: ABD-22795

This kit uses Ac-DEVD-AMC as a fluorogenic indicator for caspase-3 activity. Sufficient reagents to perform 500 assays. Using 25µl of reagents per well in a 384-well format, this kit provides sufficient reagents to perform 2,000 assays.
Anwendung: Apoptosis assay
279,00 €
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LDH Cytotoxicity Assay Kit
LDH Cytotoxicity Assay Kit

Artikelnummer: Cay601170-96

Necrosis is accompanied by mitochondrial swelling and increased plasma membrane permeability, while apoptosis involves an articulated breakdown of the cell into membrane-bound apoptotic bodies. Lactate dehydrogenase (LDH) is a soluble cytosolic enzyme that is released into the culture medium following loss of...
Schlagworte: Lactate Dehydrogenase Cytotoxicity Assay Kit
Anwendung: Cell based assays
Spezies-Reaktivität: broad
ab 105,00 €
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WST-8 Cell Proliferation Assay Kit
WST-8 Cell Proliferation Assay Kit

Artikelnummer: Cay10010199-480

Cayman's WST-8 Cell Proliferation Assay provides a tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of WST-8 by NADH produced in the mitochondria resulting in a water-soluble formazan which dissolves directly into the culture...
Anwendung: Cell based assays
ab 81,00 €
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Glycolysis Cell-Based Assay Kit
Glycolysis Cell-Based Assay Kit

Artikelnummer: Cay600450-1

Cayman's Glycolysis Cell-Based Assay Kit provides a colorimetric method for detecting L-lactate, the end product of glycolysis, produced and secreted by cultured cells. In this assay, lactate dehydrogenase catalyzes the reaction between NAD+ and lactate, yielding pyruvate and NADH. The NADH directly reduces a...
Schlagworte: Glycolysis
Anwendung: Extracellular L-lactate detection
390,00 €
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Cell Meter(TM) Phosphatidylserine Apoptosis Assay Kit *Green Fluorescence*
Cell Meter(TM) Phosphatidylserine Apoptosis Assay Kit...

Artikelnummer: ABD-22791

Designed to monitor cell apoptosis through measuring the translocation of phosphatidylserine (PS). The PS sensor used in this kit is a single fluorophore-labeled Annexin V that is specially modified to bind PS more tightly.
Schlagworte: Apopxin PS
Anwendung: Apoptosis assay
279,00 €
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Autophagy/Cytotoxicity Dual Staining Kit
Autophagy/Cytotoxicity Dual Staining Kit

Artikelnummer: Cay600140-1

Autophagy is a critical cellular process that involves the degradation and digestion of intracellular components by the lysosome. This process not only enables cells to efficiently mobilize and recycle cellular constituents, but also prevents the accumulation of damaged organelles, misfolded proteins, and invading...
Anwendung: Fluorescence
395,00 €
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Neutrophil Elastase Activity Assay Kit
Neutrophil Elastase Activity Assay Kit

Artikelnummer: Cay600610-192

Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
Schlagworte: HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Neutrophile elastase detection
Spezies-Reaktivität: human
543,00 €
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ADRA1B Reporter Assay System (human)
ADRA1B Reporter Assay System (human)

Artikelnummer: IB-IB31101

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1B (ADRA1B). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1B. In addition to ADRA1B Reporter Cells, this kit...
Schlagworte: ADRA1B, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha-1B adrenergic receptor
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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ADRA1B Reporter Assay System (human)
ADRA1B Reporter Assay System (human)

Artikelnummer: IB-IB31102

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1B (ADRA1B). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1B. In addition to ADRA1B Reporter Cells, this kit...
Schlagworte: ADRA1B, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha-1B adrenergic receptor
Anwendung: Functional activity screening
Spezies-Reaktivität: human
3.803,00 €
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ADRA1D Reporter Assay System (human)
ADRA1D Reporter Assay System (human)

Artikelnummer: IB-IB31201

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1D (ADRA1D). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1D. In addition to ADRA1D Reporter Cells, this kit...
Schlagworte: ADRA1A, ADRA1D, Alpha-1D adrenoceptor, Alpha-1D adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor...
Anwendung: Functional activity screening
Spezies-Reaktivität: human
1.448,00 €
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