Anti-phospho-Smad2 (Thr220)

Anti-phospho-Smad2 (Thr220)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG51796.50 50 µl - -

6 - 14 Werktage*

436,00 €
ARG51796.100 100 µl - -

6 - 14 Werktage*

624,00 €
 
Protein function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and... mehr
Produktinformationen "Anti-phospho-Smad2 (Thr220)"
Protein function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Schlagworte: Anti-phospho-Smad2, Anti-phospho-MADH2, Anti-phospho-SMAD2, Anti-phospho-SMAD 2, Anti-phospho-hSMAD2, Anti-phospho-JV18-1, Anti-phospho-hMAD-2, Anti-phospho-MAD homolog 2, Anti-phospho-SMAD family member 2, Anti-phospho-Mad-related protein 2
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG51796

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Peptide sequence around phosphorylation site of threonine 220 (P-E-T(p)-P-P) derived from Human Smad2
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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