Anti-phospho-p21Cip1 (Thr145)

Anti-phospho-p21Cip1 (Thr145)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG51698.50 50 µl - -

6 - 14 Werktage*

436,00 €
ARG51698.100 100 µl - -

6 - 14 Werktage*

624,00 €
 
Protein function: May be the important intermediate by which p53/TP53 mediates its role as an... mehr
Produktinformationen "Anti-phospho-p21Cip1 (Thr145)"
Protein function: May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex. [The UniProt Consortium]
Schlagworte: Anti-phospho-p21, Anti-phospho-CAP20, Anti-phospho-MDA-6, Anti-phospho-CDKN1A, Anti-phospho-CDK-interacting protein 1, Anti-phospho-Cyclin-dependent kinase inhibitor 1, Anti-phospho-Melanoma differentiation-associated protein 6
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG51698

Eigenschaften

Anwendung: IHC (paraffin)
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Peptide sequence around phosphorylation site of threonine 145 (R-Q-T(p)-S-M) derived from Human p21Cip1
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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