Anti-phospho-HSP27 (Ser78) (Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27, Stres

Anti-phospho-HSP27 (Ser78) (Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27, Stres
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
H1830-53J-FITC.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
In response to adverse changes in their environment, cells from many organisms increase the... mehr
Produktinformationen "Anti-phospho-HSP27 (Ser78) (Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27, Stres"
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSBP1 exhibits rapid increased phosphorylation in response to various mitogens, tumor promoters (e.g. phorbol esters) and calcium ionophores, and high levels are associated with carcinoma of the breast and with endometrial adenocarcinomas. Heat shock of HeLa cell cultures, or treatment with arsenite, phorbol ester, or tumor necrosis factor, causes a rapid phosphorylation of preexisting HSBP1, with Ser82 as the major site and Ser78 the minor site of phosphorylation. HSBP1 may exert phosphorylation-activated functions linked with growth signaling pathways in unstressed cells. A homeostatic function at this level could protect cells from adverse effects of signal transduction systems which may be activated inappropriately during stress. Applications: Suitable for use in FLISA and Dot Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000 , Dot Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-phospho-HSP27, Anti-phospho-SRP27, Anti-phospho-HSPB1, Anti-phospho-HspB1, Anti-phospho-HSP 27, Anti-phospho-Heat shock protein beta-1, Anti-phospho-Heat shock 27 kDa protein, Anti-phospho-28 kDa heat shock protein
Hersteller: United States Biological
Hersteller-Nr: H1830-53J-FITC

Eigenschaften

Anwendung: FLISA, Dot Blot, WB
Antikörper-Typ: Polyclonal
Konjugat: FITC
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser78 of human HSBP1 (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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