Anti-UFC1

UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1, MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]). Protein function: E1-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:15071506, PubMed:29868776). Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:15071506, PubMed:29868776). Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526). [The UniProt Consortium]