Anti-TRIM33/TIF1gamma

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A301-060A-T 10 µl (2 µg) -

2 - 8 Werktage*

164,00 €
A301-060A 100 µl -

2 - 8 Werktage*

588,00 €
 
Protein function: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear... mehr
Produktinformationen "Anti-TRIM33/TIF1gamma"
Protein function: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF- beta/BMP signaling cascade). [The UniProt Consortium]
Schlagworte: Anti-TRIM33, Anti-KIAA1113, Anti-TIF1-gamma, EC=6.3.2.-, Anti-Protein Rfg7, Anti-Ectodermin homolog, Anti-RET-fused gene 7 protein, Anti-E3 ubiquitin-protein ligase TRIM33, Anti-Tripartite motif-containing protein 33
Hersteller: Bethyl Laboratories
Hersteller-Nr: A301-060A

Eigenschaften

Anwendung: WB, IP, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse (Erwartet: rat, X. tropicalis, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, root node of taxonomy, duckbill platypus)
Immunogen: synthetic peptide. The epitope recognized by A301-060A-T maps to a region between residue 1077 and the C-terminus (residue 1127) of human tripartite motif-containing 33 (transcriptional intermediary factor 1 gamma) using the numbering given in entry NP_056990.3 (GeneID 51592).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-TRIM33/TIF1gamma"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen