Anti-TPSAB1

WB 1:500 - 1:2000, IHC 1:50 - 1:200. Protein function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315). [The UniProt Consortium]