Anti-Stathmin 2 (Stathmin-2, STMN2, Protein SCG10, Superior Cervical Ganglion-10 Protein, SCG10, SCG

Stathmin-2 (STMN2), also known as superior cervical ganglion 10 protein (SCG10), is a 19kD microtubule-destabilizing protein that is preferentially expressed in neurons. It promotes neuronal proliferation and migration as well as neurite outgrowth. Stathmin-2 contains a membrane attachment region aa1-26, a regulatory domain aa39-96, and an overlapping coiled-coil domain aa75-179. It is subject to phosphorylation of multiple serines within the regulatory domain. Within aa26-179, human Stathmin-2 shares 100% and 99% aa sequence identity with mouse and rat Stathmin-2. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.05ug/ml, Immunohistochemistry: 8-25ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.