Anti-Splicing regulator SDE2

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-RQ7495 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Splicing regulator SDE2 enables damaged... mehr
Produktinformationen "Anti-Splicing regulator SDE2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Splicing regulator SDE2 enables damaged DNA binding activity. Involved in several processes, including cellular response to UV, mitotic G1 DNA damage checkpoint signaling, and protein ubiquitination. Located in several cellular components, including Golgi apparatus, cytosol, and nuclear speck. Protein function: Inhibits translesion DNA synthesis by preventing monoubiquitination of PCNA, this is necessary to counteract damage due to ultraviolet light-induced replication stress (PubMed:27906959). SDE2 is cleaved following PCNA binding, and its complete degradation is necessary to allow S-phase progression following DNA damage (PubMed:27906959). [The UniProt Consortium]
Schlagworte: Anti-SDE2, Anti-C1orf55, Anti-Splicing regulator SDE2, Anti-Replication stress response regulator SDE2, Splicing regulator SDE2 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: RQ7495

Eigenschaften

Anwendung: WB, IF, FC, IHC (paraffin), Direct ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: E. coli-derived recombinant human protein (amino acids I10-K447)
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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