Anti-SNX1 (Sorting Nexin 1, SNX-1, Sorting Nexin 1A, SNX1A, HsT17379, MGC8664)

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. , Recommended Dilutions: Peptide ELISA Titer: 1:64,000, Western Blot: 1-3ug/ml ~75kD band observed in Human lysates of cell line HeLa (calculated MW of 59.1kD according to NP_003090.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.